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Table 6 Summarization of recent studies of risks of surgical site infection after pancreaticoduodenectomy

From: Predictors of surgical site infection after pancreaticoduodenectomy

Author (year)

Type of study

No. of patients

Incidence of SSI (%)

Percent of malignancy (%)

Risk factors of surgical site infection

Poluk K. E (2016) [37]

Single center retrospective

679

17.2

–

Pre-operative biliary drainage,

Neoadjuvant chemotherapy

Zhang L (2016) [9]

Single center retrospective

212

29a

80

Pancreatic fistula,

Blood transfusion

Barreto S. G (2015) [7]

Single center retrospective

277

35

81

Pre-operative biliary stent insertion,

Non-diabetic endocrine co-morbidity.

De Pastena M (2017) [17]

Single center retrospective

893

45.8†

–

Pre-operative biliary drainage

Sugiura T (2012) [8]

Single center retrospective

408

51

90

Long operative time,

High Body Mass Index,

Pancreatic fistula,

Semi-close suction drain,

Main pancreatic duct < 3 mm,

Abdominal wall fat thickness > 10 mm.

Burkhart R. A (2017) [2]

Single center retrospective

394

19.8

71.1

Pre-operative biliary drainage, neoadjuvant therapy, prior abdominal surgery

Shinkawa H (2018) [10]

Single center retrospective

106

14.2

–

Nutritional risk index,

Pancreatic fistula

Gavazzi F (2016) [35]

Single center

retrospective

180

52.3

86

Pre-operative biliary stent,

Cardiac disease, BMI > 25 mg/m2

Okano K (2015) [30]

Multi center

retrospective

4147

27.1

90

Male sex, age 70 years or more,

Body mass index at least 25 kg/m2,

Other previous malignancy,

Liver disease,

Bile contamination,

Duration of surgery 7 h or longer, Intraoperative blood transfusion,

Soft pancreas

  1. a Overall infectious complication
  2. - Not stated