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Table 3 Variable associated with organ/space surgical site infection (SSI)

From: Predictors of surgical site infection after pancreaticoduodenectomy

SSIUnivariateMultivariate
OR (95% CI)p valueOR (95% CI)p value
Age in years, mean ± SD1.002 (0.96–1.03)0.891  
BMI, median (range)1.104 (1.01–1.20)0.0241.107 (0.99–1.22)0.057
Sex, n (%)
 Male1   
 Female1.507 (0.71–3.18)0.281  
Comorbidities, n (%)
 Diabetes mellitus0.284 (0.09–0.84)0.024  
 Hypertension1.263 (0.59–2.67)0.542  
 Dyslipidemia0.765 (0.32–1.80)0.541  
 Renal insufficiency1.453 (0.15–13.42)0.742  
ASA class, n (%), n = 242
 I1   
 II0.144 (0.02–0.81)0.029  
 III0.169 (0.03–0.90)0.038  
 IV0.333 (0.03–3.20)0.341  
Smoking, n (%)0.531 (0.20–1.35)0.187  
Previous biliary intervention, n (%)1.864 (0.79–4.35)0.150  
WBC, mean ± SD0.933 (0.80–1.08)0.369  
Platelet ×103, median (range)0.741 (0.50–1.08)0.125  
Hemoglobin in g/dL, median (range)0.997 (0.85–1.15)0.970  
BUN in mg/dL, median (range)1.001 (0.94–1.06)0.967  
Creatinine in mg/dL, median (range)0.734 (0.25–2.07)0.561  
Total bilirubin in mg/d/L, median (range)0.981 (0.92–1.04)0.538  
Albumin in g/L, mean ± SD0.951 (0.89–1.01)0.128  
Preoperative cholangitis, n(%)12.193 (1.07–138.54)0.04410.722 (2.31–49.75)0.002
Operative time in min, median (range)1.126 (0.83–1.51)0.428  
Blood loss in ml, median (range)1.264 (1.01–1.59)0.046  
Complications, n (%)
 Pancreatic fistula    
  No1 1 
  Yes8.399 (3.10–22.71)0.0006.531 (2.30–18.51)0.000
 Bile leakage2.482 (0.73–8.44)0.145  
 Delayed gastric emptying1.733 (0.53–5.63)0.360  
 Chyle leakage1.978 (0.38–10.24)0.416  
Diagnosis, n (%)
 Benign1   
 Malignant0.952 (0.41–2.18)0.908  
  1. SSI Surgical site infection, OR Odds ratio, CI Confidence interval, BMI Body mass index, ASA American Society of Anesthesiologists, WBC White blood cell count, BUN Blood urea nitrogen