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Table 2 Variables associated with incisional surgical site infection (SSI)

From: Predictors of surgical site infection after pancreaticoduodenectomy

SSIUnivariateMultivariate
OR (95% CI)p valueOR (95% CI)p value
Age in years, mean ± SD1.006 (0.97–1.03)0.657  
BMI, median (range)1.015 (0.94–1.09)0.677  
Sex, n (%)
 Male1   
 Female0.751 (0.41–1.37)0.352  
Comorbidities, n (%)
 Diabetes mellitus0.737 (0.37–1.43)0.368  
 Hypertension1.246 (0.68–2.27)0.473  
 Dyslipidemia0.638 (0.31–1.29)0.214  
 Renal insufficiency1.690 (0.30–9.47)0.550  
ASA class, n (%), n = 242
 II1   
 III0.833 (0.45–1.52)0.554  
Smoking, n (%)1.504 (0.81–2.78)0.195  
Previous biliary intervention, n (%)3.182 (1.47–6.87)0.0033.041 (1.36–6.79)0.007
WBC, mean ± SD0.958 (0.85–1.08)0.496  
Platelet ×103, median (range)0.794 (0.58–1.07)0.130  
Hemoglobin in g/dL, median (range)1.058 (0.94–1.17)0.303  
BUN in mg/dL, median (range)0.999 (0.95–1.05)0.971  
Creatinine in mg/dL, median (range)1.082 (0.84–1.38)0.532  
Total bilirubin in mg/d/L, median (range)0.971 (0.92–1.02)0.260  
Albumin in g/L, mean ± SD0.999 (0.94–1.05)0.975  
Pre-operative cholangitis, n(%)3.375 (0.20–54.82)0.3922.647 (0.75–9.23)0.127
Operative time in min, median (range)1.205 (0.96–1.50)0.098  
Blood loss in ml, median (range)0.980 (0.74–1.28)0.888  
Complications, n (%)
 Pancreatic fistula
  No1 1 
  Yes3.250 (1.73–6.09)0.0002.783 (1.43–5.38)0.002
 Bile leakage2.117 (0.73–6.10)0.165  
 Delayed gastric emptying3.006 (1.28–7.06)0.012  
 Chyle leakage2.586 (0.84–7.93)0.097  
Diagnosis, n (%)
 Benign1   
 Malignant1.040 (0.58–1.84)0.892  
  1. SSI Surgical site infection, OR Odds ratio, CI Confidence interval, BMI Body mass index, ASA American Society of Anesthesiologists, WBC White blood cell count, BUN Blood urea nitrogen