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Table 3 Transplant outcomes in CLKT and SLKT groups

From: Outcomes of liver–kidney transplantation in patients with primary hyperoxaluria: an analysis of the scientific registry of transplant recipients database

 

CLKT (n = 181)

SLKT (n = 20)

P value

Liver

 Rejection episode

15 (12.9%)

1 (12.5%)

0.898

 Graft failure

7 (3.9%)

0 (0.0%)

0.371

Cause of graft failure

 Primary graft failure

2 (33.3%)

  

 Vascular thrombosis

2 (33.3%)

  

 Acute rejection

1 (16.7%)

  

 Other

1 (16.7%)

  

Recipient discharge labs (Median, IQR)

 AST (U/L)

44.0 (22.3,61.8)

35.5 (26.0,58.3)

0.912

 ALT (U/L)

44.5 (21., 97.5)

38 (20, 88.5)

0.58

 Alkaline phosphate (U/L)

250.5 (191, 501.8)

441.5 (254.0, 891.3)

0.083

 Albumin (g/dL)

3.0 (2.43, 3.38)

2.9 (2.0, 3.6)

0.626

 Serum creatinine (mg/dL)

1.4 (0.7, 2.4)

4.4 (3.7, 6.25)

0.018

Median days from transplant until discharge (IQR)

19 (9,34)

26 (14,33)

0.238

Kidney

 Rejection episode

5 (4.3%)

0 (0.0%)

0.505

 Graft failure

15 (8.3%)

3 (15.0%)

0.321

Cause of graft failure

 Acute rejection

0 (0.0%)

1 (33.3%)

 

 Primary graft failure

3 (20.0%)

1 (33.3%)

 

 Graft thrombosis

2 (13.3%)

1 (33.3%)

 

 Infection

1 (6.7%)

0 (0.0%)

 

 Urological Complications

1 (6.7%)

0 (0.0%)

 

 Recurrent diseases

1 (6.7%)

0 (0.0%)

 

 Primary non-function

2 (13.3%)

0 (0.0%)

 

 Unknown

5 (33.3%)

0 (0.0%)

 

Serum creatinine at discharge (mg/dL, median, IQR)

1.3 (0.7,2.3)

0.9 (0.45,1.4)

0.161

Median number of days from transplant until discharge (IQR)

19 (9,34)

10 (5,21)

0.009

Median interval between LT and KT (month, IQR)

 

10.5 (6.25, 24.25)

 
  1. CLKT Combined liver and kidney transplant, SLKT Sequential liver and kidney transplant, IQR Interquartile range, BMI Body mass index, CNS Central nervous system, LT Liver transplantation, KT Kidney transplantation, AST Aspartate aminotransferase, ALT Alanine aminotransferase