Skip to main content

Table 1 Baseline characteristics of patients and tumors

From: The outcomes of modified endoscopic mucosal resection and endoscopic submucosal dissection for the treatment of rectal neuroendocrine tumors and the value of endoscopic morphology classification in endoscopic resection

 

Total(n = 338)

m-EMR(n = 79)

ESD(n = 259)

P value

Patient Characteristics

 Age, y

   

0.376

  Mean ± SD

49.49 ± 10.8

50.4 ± 11.1

49.2 ± 10.7

 

  Median (range)

49(15–80)

49(16–77)

49(15–80)

 

 Sex, n (%)

   

0.762

  Male

206(60.9%)

47(59.5%)

159 (61.4%)

 

  Female

132(39.1%)

32(40.5%)

100 (38.6%)

 

Tumor Characteristics

 Lesion size, mm

   

0.004*

  Mean ± SD

6.8 ± 2.9

5.8 ± 1.9

7.1 ± 3.1

 

  Median (range)

6.0(2–18)

6.0 (2–10)

6.0 (2–18)

 

 Lesion size group, n (%)

   

0.011*

  < 10 mm

275(81.4%)

72(91.1%)

203(78.4%)

 

  ≥ 10 mm

63(18.6%)

7(8.9%)

56(21.6%)

 

 Location, n(%)

  Upper

22(6.5%)

6(7.6%)

16(6.2%)

0.552

  Middle

170(50.3%)

43(54.4%)

127(49.0%)

 

  Lower

146(43.2%)

30(38.0%)

116(44.8%)

 

 Histopathological grade, n (%)

   

0.681

  Grade 1

286(84.6%)

68(86.1%)

218(84.2%)

 

  Grade 2

52(15.4%)

11(13.9%)

41(15.8%)

 

 Invasion layer, n (%)

   

0.636

  Mucosal

75(22.2%)

16(20.3%)

59(22.8%)

 

  Submucosal

263(77.8%)

63(79.7%)

200(77.2%)

 

 Endoscopic morphology, n (%)

  Ia

39(11.5%)

6(7.6%)

33(12.7%)

0.146

  Ib

230(68.1%)

59(74.7%)

171(66.0%)

 

  II

51(15.1%)

13(16.4%)

38(14.7%)

 

  III

18(5.3%)

1(1.3%)

17(6.6%)

 

Outcomes

 Procedure time, min

   

0.000*

  Mean ± SD

15.3 ± 9.4

9.1 ± 4.4

17.2 ± 9.7

 

  Median (range)

12.0 (3–56)

8.0 (3–26)

15.0(4–56)

 

 En bloc resection, n (%)

334(98.8%)

78 (98.7%)

256 (98.8%)

1.000

 Complete resection(R0), n (%)

310(91.7%)

72(91.1%)

238(91.9%)

0.832

 Procedure-related adverse events, n (%)

9(2.7%)

2(2.6%)

7(2.7%)

0.572

  Postprocedural bleeding

7(2.1%)

1(1.3%)

6(2.3%)

 

  Perforation

2(0.6%)

1(1.3%)

1(0.4%)

 

 Operation involving incomplete resectiona, n (%)

7(2.1%)

1(1.3%)

6(2.3%)

0.902

  1. ESD Endoscopic submucosal dissection, m-EMR Modified endoscopic mucosal resection, SD standard deviation
  2. *p < 0.05
  3. aOne patient in the m-EMR group and 4 patients in the ESD group underwent subsequent surgery, two patient in the ESD group underwent additional ESD due to the positive resection margins