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Table 1 Characteristics of the included studies-Part I

From: The risk of rheumatoid arthritis among patients with inflammatory bowel disease: a systematic review and meta-analysis

Study

Country

Design/study duration

Sample source

Definition criteria

 

IBD

RA

Aletaha-2019 [17]

USA

Retrospective Cohort/10 years

MarketScan Commercial Claims and Encounters database

≥2 claims at least 30 days apart with ICD-9 codes (555.x, 556.x)

≥2 claims at least 30 days apart with ICD-9 codes (714, 714.0, 714.8, 714.89, 714.9)

Bae-2017a [14]

Korea

Cross-sectional/NA

National Health Insurance Database

≥5 health contacts due to UC/ CD as the principal diagnosis with ICD-9 codes (K50, K51)

≥5 health contacts due to RA as the principal diagnosis with ICD-9 codes (M05, M06)

Burisch-2019 [16]

Denmark

Retrospective Cohort/10 years

National

Patient Registry

≥2 diagnoses with ICD-8 codes (563.01, 563.19) or ICD-10 codes (K50, K51)

≥1 diagnosis with ICD-10 codes (M05, M06.0, M06.8, M06.9)

Cohen-2008-1 [16]

USA

Cross-Sectional/ NA

IMS Health Integrated Administration Claims Database

≥1 claim with ICD-9 codes (555.x, 556.x)

≥1 claim with ICD-9 codes (714.x)

Cohen-2008-2 [13]

USA

Cross-Sectional/ NA

MarketScan Commercial Claims and Encounters Database

≥1 claim with ICD-9 codes (555.x, 556.x)

≥1 claim with ICD-9 codes (714.x)

Halling-2017a [12]

Denmark

Cross-Sectional/ NA

National

Patient Registry

ICD-10 codes (K50, K51)

ICD-10 codes

Kappelman-2011 [11]

USA

Cross-Sectional/ NA

PharMetrics Patient-Centric Database

≥3 health contacts with associated ICD-9 codes (555.x, 556.x), or ≥ 1 claim with associated medication history

ICD-9 codes

Park-2019 [15]

Korea

Retrospective cohort/4 years

National Health Insurance Database

ICD-10 codes (K50, K51) and registration codes (V130, V131) for the rare/intractable disease patient-support program

ICD-10 codes and registration codes for the rare/intractable disease patient-support program

Puolakka-2014 [19]

Finland

Case-control/4 years

National Registry of the Social Insurance Institution

ICD-10 codes (K50, K51)

ICD-10 codes (M05, M06)

Kronzer-2019 [18]

USA

Case-control/10 years

Single-center biobank

Questionnaire

≥2 diagnoses at least 30 days apart with ICD-9 codes (714.0, 714.9) plus use of a disease modifying antirheumatic drug

Weng-2007 [10]

USA

Cross-sectional/NA

Northern California region of the Kaiser Permanente Medical Care Plan

≥2 diagnoses with ICD-9 codes (555.x, 556.x)

≥2 diagnoses with ICD-9 codes (714.0, 714.3x)

Yang-2018a [9]

Korea

Cross-Sectional/NA

National Health Insurance Database

ICD-10 codes (K50, K51) and registration codes (V130, V131) for the rare/intractable disease patient-support program

ICD-10 codes (M05, M06)

  1. CD Crohn Disease, IBD Inflammatory Bowel Diseases, NM Not Mentioned, ICD-8 International Classification of Disease 8th revision, ICD-9 International Classification of Disease 9th revision, ICD-10 International Classification of Disease 10th revision, NA Not Apply, RA Rheumatoid Arthritis, UC Ulcerative Colitis
  2. aThese cross-sectional studies were not included in the statistical meta-analysis as the populations in these studies overlapped with those in the other cohort studies