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Table 3 Multivariate Hazards regression analysis of the relationship between different dose of albumin/red blood cell infusion before rebleeding and rebleeding

From: The impact of albumin infusion on the risk of rebleeding and in-hospital mortality in cirrhotic patients admitted for acute gastrointestinal bleeding: a retrospective study of a single institute

Pre-ALB infusion

 

(0, 40 g]

P value

> 40 g

P value

Unadjusted

0.879 (0.561–1.376)

0.572

0.575 (0.285–1.160)

0.122

Adjusted for albumin, Child-Pugh class

0.500 (0.312–0.800)

0.004

0.279 (0.134–0.580)

< 0.001

Multivariable aadjusted

0.469 (0.269-0.793)

0.006

0.272 (0.115-0.576)

0.001

Pre-RBC infusion

 

(4–8 units]

P value

>  8 units

P value

 Unadjusted

3.556 (2.369–5.338)

< 0.001

5.654 (2.913–10.975)

< 0.001

 Adjusted for hemoglobin,

Child-Pugh class

3.497 (2.229–5.485)

< 0.001

5.709 (2.852–11.426)

< 0.001

 Multivariable a adjusted

1.888 (1.144-3.067)

0.011

2.634 (1.142-5.812)

0.019

  1. aadjust for Child-Pugh classification, presence of encephalopathy and ascties, bleed from unidentified lesion, the initial application of tamponade, values of bilirubin, albumin and prothrombin time, endoscopic treatments