Non-steroidal anti-inflammatory drug-induced enteropathy as a major risk factor for small bowel bleeding: a retrospective study

Table 3 Rebleeding cases

No.	Indication for capsule endoscopy	Cause of small bowel bleeding	Final diagnosis	Timing of rebleeding after diagnosis	Specific therapy	Treatment outcome
1	Bloody stool	Ulcer	Crohn’s disease	23 days	Thiopurine	Persistent IDA^c
2	Bloody stool	Diffuse scar change	Radiation ileitis^a	87 days	Surgery	No further bleeding
3	Bloody stool	Ulcer	Crohn’s disease	117 days	5-aminosalicylic acid	Persistent IDA^c
4	Bloody stool	Ulcer with stricture	Radiation ileitis^a	49 days	Iron replacement	Follow-up loss
5	IDA	Ulcer	Intestinal Tbc^b	146 days	Anti-Tbc medication	Recovered IDA
6	IDA	Ulcer with stricture	NSAID-induced enteropathy	15 days	Surgery	Recovered IDA
7	Bloody stool	Angioectasia	Angioectasia	330 days	Surgery	No further bleeding

^a Indication for radiation therapy was uterine cervical cancer
^b The patient who was considered as having Crohn’s disease initially, presented with multiple lymphadenopathy and was finally diagnosed with tuberculosis
^cPatient No.1 was given methotrexate instead of thiopurine and no recurrence of anemia has been reported since then; Patient No.3 underwent resection of a short segment of the small bowel and anemia has not recurred so far
IDA Iron deficiency anemia; Tbc Tuberculosis; NSAID Nonsteroidal anti-inflammatory drug

ISSN: 1471-230X