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Table 1 The baseline characteristics of patients with ACLF

From: Nomogram based on blood lipoprotein for estimation of mortality in patients with hepatitis B virus-related acute-on-chronic liver failure

 

Development group (n = 260)

Validation group(n = 133)

p

Age (year)

45 ± 12

45 ± 13

0.571

Gender (male/female)

222/38

108/25

0.310

Red blood cell count (× 1012/L)

3.93 ± 0.91

3.88 ± 0.95

0.620

White blood cell count (×109/L)

8.08 ± 3.56

9.43 ± 7.78

0.058

Hemoglobin (g/dL)

119.92 ± 23.35

118.58 ± 22.86

0.587

Albumin (g/L)

31.76 ± 4.54

31.42 ± 4.32

0.469

Alanine aminotransferase (U/L)

707.38 ± 877.45

649.70 ± 855.85

0.534

Prothrombin activity (%)

29.28 ± 7.57

27.87 ± 7.84

0.085

INR

2.75 ± 1.00

3.05 ± 1.27

0.019

Creatinine (μmol/L)

78.27 ± 44.77

85.84 ± 70.73

0.262

Total bilirubin (μmol/L)

378.86 ± 168.36

376.05 ± 158.08

0.871

TC (mmol/L)

2.44 ± 1.31

2.42 ± 1.05

0.849

TG (mmol/L)

0.86 ± 0.52

0.96 ± 0.51

0.056

HDLC (mmol/L)

0.19 ± 0.18

0.18 ± 0.17

0.546

LDLC (mmol/L)

1.10 ± 0.60

1.06 ± 0.65

0.568

MELD scores, median (IQR)

25.98 (23.13, 29.4)

26.46 (24.16, 31.19)

0.055

Ascites (yes/no)

167/93

95/38

0.175

mortality (yes/no)

77/183

37/96

0.726

  1. Abbreviations: INR international normalized ratio, TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol