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Table 2 Histological Characteristics with Respect to Depth of Invasion, and Comparison of LVI-positivity Rates between H-E- and D2-40-/CD31-stained Specimens

From: Use of Immunostaining for the diagnosis of Lymphovascular invasion in superficial Barrett’s esophageal adenocarcinoma

Depth of invasion and numberHistological typeH-E stainingImmunostainingP-value
tub1tub2porLy+V+LVI+ (%)D2-40 Ly+CD31 V+LVI+ (%)
T1aSMM7610000 (0)000 (0) 
LPM2110000 (0)000 (0) 
DMM121020000 (0)000 (0) 
T1bSM14130101 (25)303 (75) 
SM27151212 (28.6)222 (28.6) 
SM39252424 (44.4)425 (55.6) 
Total41     7 (17.1)  10 (24.4)0.587
  1. H-E Hematoxylin and eosin, SMM superficial muscularis mucosa, LPM lamina propria, DMM deep muscularis mucosa, SM submucosa