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Table 1 Comparision between the mucosal healing group (MH Group) and non-mucosal healing group (NMH Group) before treatment

From: Relationship between mucosal healing by tacrolimus and relapse of refractory ulcerative colitis: a retrospective study

 

MH Group

n = 41

NMH Group

n = 14

p-value

Data before PSL administration

 CAI

13.3 (9–19)

13.1 (10–17)

0.493

 Hb (g/dl)

11 (7.5–12.9)

12.6 (7.9–15.1)

0.19

 Alb (g/dl)

3.4 (1.9–4.4)

3.4 (2–4.6)

0.889

 CRP (mg/dl)

3.9 (0.2–22.6)

2.9 (0.04–11.9)

0.636

 Mayo scorea

2.9 (2–3)

3 (3)

0.341

 UCEIS scorea

6.6 (4–8)

7.4 (6–8)

0.236

Data before TAC administration

 CAI

12.9 (7–19)

13.4 (11–17)

0.593

 Hb (g/dl)

12 (7.5–14.9)

12.9 (8.1–15.1)

0.191

 Alb (g/dl)

3.3 (1.7–4.4)

3.3 (2–4.6)

0.838

 CRP (mg/dl)

3.5 (0.04–24.1)

2.6 (0.04–10.4)

0.525

 Mayo score

2.9 (2–3)

3 (3)

0.306

 UCEIS score

6.7 (4–8)

7.2 (6–8)

0.136

Time to achieve the target TAC trough level (days)

3.1 (1–10)

4.5 (1–9)

0.07

  1. Data are expressed as the mean ± standard deviation or the number of patients
  2. Alb albumin, CRP C-reactive protein, Hb hemoglobin, Mayo scar Mayo endoscopic score, ns not significant, PSL prednisolone, TAC tacrolimus, TNFα, UCEIS ulcerative colitis endoscopic index of severity
  3. aColonoscopy before PSL administration was performed in 33 patients in the MH group and 9 patients in the NMH group