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Table 1 Comparision between the mucosal healing group (MH Group) and non-mucosal healing group (NMH Group) before treatment

From: Relationship between mucosal healing by tacrolimus and relapse of refractory ulcerative colitis: a retrospective study

  MH Group
n = 41
NMH Group
n = 14
p-value
Data before PSL administration
 CAI 13.3 (9–19) 13.1 (10–17) 0.493
 Hb (g/dl) 11 (7.5–12.9) 12.6 (7.9–15.1) 0.19
 Alb (g/dl) 3.4 (1.9–4.4) 3.4 (2–4.6) 0.889
 CRP (mg/dl) 3.9 (0.2–22.6) 2.9 (0.04–11.9) 0.636
 Mayo scorea 2.9 (2–3) 3 (3) 0.341
 UCEIS scorea 6.6 (4–8) 7.4 (6–8) 0.236
Data before TAC administration
 CAI 12.9 (7–19) 13.4 (11–17) 0.593
 Hb (g/dl) 12 (7.5–14.9) 12.9 (8.1–15.1) 0.191
 Alb (g/dl) 3.3 (1.7–4.4) 3.3 (2–4.6) 0.838
 CRP (mg/dl) 3.5 (0.04–24.1) 2.6 (0.04–10.4) 0.525
 Mayo score 2.9 (2–3) 3 (3) 0.306
 UCEIS score 6.7 (4–8) 7.2 (6–8) 0.136
Time to achieve the target TAC trough level (days) 3.1 (1–10) 4.5 (1–9) 0.07
  1. Data are expressed as the mean ± standard deviation or the number of patients
  2. Alb albumin, CRP C-reactive protein, Hb hemoglobin, Mayo scar Mayo endoscopic score, ns not significant, PSL prednisolone, TAC tacrolimus, TNFα, UCEIS ulcerative colitis endoscopic index of severity
  3. aColonoscopy before PSL administration was performed in 33 patients in the MH group and 9 patients in the NMH group