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Table 4 Clinical data of the acute pancreatitis patient cohort based on H/L ratio

From: High-density lipoprotein cholesterol to low-density lipoprotein cholesterol ratio in early assessment of disease severity and outcome in patients with acute pancreatitis admitted to the ICU

ParametersH/L ratio < 0.465 (n = 86)H/L ratio > 0.465 (n = 80)P
Demographic Data
 Age, mean (SD),y45.71 (13.67)49.18 (16.20)0.141
 Male, n (%)45 (52.33)52 (65.00)0.098
 Etiology, n (%)  0.031
  Biliary36 (41.86)35 (43.80) 
  Hyperlipidemia24 (27.91)10 (12.50) 
  Others26 (30.23)35 (43.80) 
Underlying medical conditions
 Hypertension, n (%)6 (6.97)18 (22.50)0.004
 Diabetes Mellitus, n (%)14 (16.28)14 (17.50)0.834
 Severity, n (%)  0.034
  Moderately severe19 (22.09)8 (10.00) 
  Severe67 (77.91)72 (90.00) 
APACHEIIScore*, mean (SD)17.99 (6.50)20.50 (7.85)0.027
Ranson’s Score*, mean (SD)4.18 (1.46)4.30 (1.64)0.635
CHOL, mean (SD), mmol/L3.63 (2.61)3.20 (2.96)0.323
HDL-C, mean (SD), mmol/L0.33 (0.17)0.44 (0.36)0.015
LDL-C, mean (SD), mmol/L1.25 (0.72)0.59 (0.51)< 0.001
H/L ratio, mean (SD)0.28 (0.09)1.14 (1.15)< 0.001
Ventilation free days#, mean (SD), d16.13 (9.16)17.57 (8.71)0.045
Renal replacement therapy, n (%)6 (6.97)21 (26.25)0.001
ICU LOS, mean (SD), d25.86 (26.62)21.02 (17.43)0.163
Hospital LOS, mean (SD), d33.40 (22.88)27.85 (23.50)0.126
Complete blood count*
 RBC, mean (SD),× 109/L3.15 (0.69)3.21 (1.00)0.649
 HGB, mean (SD), g/L95.34 (22.37)95.12 (27.54)0.955
 HCT, mean (SD), L/L0.29 (0.06)0.29 (0.08)0.844
 PLT, mean (SD),×109/L156.36 (104.59)144.06 (111.11)0.463
 WBC, mean (SD),×109/L11.95 (5.18)12.74 (6.52)0.389
Coagulation test*
 APTT, mean (SD), s36.57 (10.40)44.76 (19.51)0.001
 Fib, mean (SD), g/L5.07 (1.90)4.13 (1.77)0.001
 TT, mean (SD), s19.52 (12.51)18.05 (2.65)0.290
Arterial Blood Gas Test*
 pH, mean (SD)7.36 (0.27)7.28 (0.46)0.193
 PaO2, mean (SD), mmHg84.18 (29.66)95.73 (41.32)0.045
 PaCO2, mean (SD), mmHg40.25 (6.77)39.50 (9.84)0.573
 Lac, mean (SD), mmol/L1.63 (0.49)1.96 (1.02)0.012
Biochemical analysis*
 PCT, mean (SD), ng/mL6.82 (16.18)10.44 (17.42)0.184
 CRP, mean (SD), mg/L189.16 (105.01)183.75 (92.43)0.747
 IL-6, mean (SD), ng/mL287.52 (481.42)459.90 (752.33)0.114
 Serum sodium, mean (SD), mmol/L137.66 (6.60)140.05 (7.72)0.035
 Serum potassium, mean (SD), mmol/L3.75 (0.41)3.81 (0.50)0.368
 Serum chloride, mean (SD), mmol/L108.05 (6.33)109.45 (6.95)0.181
 TB, mean (SD), mmol/L40.29 (57.13)41.17 (53.33)0.918
 DB, mean (SD), mmol/L30.97 (47.86)33.20 (46.99)0.763
 ALT, mean (SD), mmol/L50.06 (167.93)92.73 (199.87)0.140
 AST, mean (SD), mmol/L78.55 (228.91)164.60 (465.49)0.137
 ALB, mean (SD), mmol/L30.74 (5.11)29.41 (6.21)0.135
 Glu, mean (SD), mmol/L10.07 (3.11)10.06 (3.72)0.982
 Crea, mean (SD), mmol/L141.64 (140.04)212.41 (196.63)0.009
 Cys-c, mean (SD), mmol/L1.43 (0.83)1.93 (1.35)0.005
 GGT, mean (SD), mmol/L108.49 (123.97)91.62 (108.70)0.352
 TG, mean (SD), mmol/L3.56 (2.26)4.07 (5.21)0.419
  1. APACHE Acute Physiology and Chronic Health Evaluation, RBC Red blood cell, HGB Hemoglobin, HCT Hematocrit, MCV Mean corpuscular volume, MCH Mean corpuscular hemoglobin, MCHC Mean corpuscular hemoglobin concentration, RDW Red blood cell distribution width, PLT Platelets, WBC white blood cell, INR International normalized ratio, PT prothrombin time, APTT Activated partial thromboplastin time, Fib fibrinogen, TT Thrombin time, PaO2 Arterial oxygen partial pressure, PaCO2 Arterial carbon dioxide partial pressure, BE Base excess, Lac lactate, PCT Procalcitonin, TB Total bilirubin, DB Direct bilirubin, ALT Alanine Aminotransferase, AST Aspartate Aminotransferase, ALP Alkaline Phosphatase, TP Total protein, ALB Albumin, Glu Glucose, Crea Creatinine, Cys-c Cystatin C, GGT Gamma-Glutamyl Transferase, TG Triglycerides, CHOL cholesterol, HDL-C High-density lipoprotein cholesterol, LDL-C Low-density lipoprotein cholesterol, H/L HDL-C/ LDL-C, LOS length of stay, IQR interquartile range