Table 4 Clinical data of the acute pancreatitis patient cohort based on H/L ratio
Parameters | H/L ratio < 0.465 (n = 86) | H/L ratio > 0.465 (n = 80) | P |
|---|---|---|---|
Demographic Data | |||
Age, mean (SD),y | 45.71 (13.67) | 49.18 (16.20) | 0.141 |
Male, n (%) | 45 (52.33) | 52 (65.00) | 0.098 |
Etiology, n (%) | 0.031 | ||
Biliary | 36 (41.86) | 35 (43.80) | |
Hyperlipidemia | 24 (27.91) | 10 (12.50) | |
Others | 26 (30.23) | 35 (43.80) | |
Underlying medical conditions | |||
Hypertension, n (%) | 6 (6.97) | 18 (22.50) | 0.004 |
Diabetes Mellitus, n (%) | 14 (16.28) | 14 (17.50) | 0.834 |
Severity, n (%) | 0.034 | ||
Moderately severe | 19 (22.09) | 8 (10.00) | |
Severe | 67 (77.91) | 72 (90.00) | |
APACHEIIScore*, mean (SD) | 17.99 (6.50) | 20.50 (7.85) | 0.027 |
Ranson’s Score*, mean (SD) | 4.18 (1.46) | 4.30 (1.64) | 0.635 |
CHOL, mean (SD), mmol/L | 3.63 (2.61) | 3.20 (2.96) | 0.323 |
HDL-C, mean (SD), mmol/L | 0.33 (0.17) | 0.44 (0.36) | 0.015 |
LDL-C, mean (SD), mmol/L | 1.25 (0.72) | 0.59 (0.51) | < 0.001 |
H/L ratio, mean (SD) | 0.28 (0.09) | 1.14 (1.15) | < 0.001 |
Ventilation free days#, mean (SD), d | 16.13 (9.16) | 17.57 (8.71) | 0.045 |
Renal replacement therapy, n (%) | 6 (6.97) | 21 (26.25) | 0.001 |
ICU LOS, mean (SD), d | 25.86 (26.62) | 21.02 (17.43) | 0.163 |
Hospital LOS, mean (SD), d | 33.40 (22.88) | 27.85 (23.50) | 0.126 |
Complete blood count* | |||
RBC, mean (SD),× 109/L | 3.15 (0.69) | 3.21 (1.00) | 0.649 |
HGB, mean (SD), g/L | 95.34 (22.37) | 95.12 (27.54) | 0.955 |
HCT, mean (SD), L/L | 0.29 (0.06) | 0.29 (0.08) | 0.844 |
PLT, mean (SD),×109/L | 156.36 (104.59) | 144.06 (111.11) | 0.463 |
WBC, mean (SD),×109/L | 11.95 (5.18) | 12.74 (6.52) | 0.389 |
Coagulation test* | |||
APTT, mean (SD), s | 36.57 (10.40) | 44.76 (19.51) | 0.001 |
Fib, mean (SD), g/L | 5.07 (1.90) | 4.13 (1.77) | 0.001 |
TT, mean (SD), s | 19.52 (12.51) | 18.05 (2.65) | 0.290 |
Arterial Blood Gas Test* | |||
pH, mean (SD) | 7.36 (0.27) | 7.28 (0.46) | 0.193 |
PaO2, mean (SD), mmHg | 84.18 (29.66) | 95.73 (41.32) | 0.045 |
PaCO2, mean (SD), mmHg | 40.25 (6.77) | 39.50 (9.84) | 0.573 |
Lac, mean (SD), mmol/L | 1.63 (0.49) | 1.96 (1.02) | 0.012 |
Biochemical analysis* | |||
PCT, mean (SD), ng/mL | 6.82 (16.18) | 10.44 (17.42) | 0.184 |
CRP, mean (SD), mg/L | 189.16 (105.01) | 183.75 (92.43) | 0.747 |
IL-6, mean (SD), ng/mL | 287.52 (481.42) | 459.90 (752.33) | 0.114 |
Serum sodium, mean (SD), mmol/L | 137.66 (6.60) | 140.05 (7.72) | 0.035 |
Serum potassium, mean (SD), mmol/L | 3.75 (0.41) | 3.81 (0.50) | 0.368 |
Serum chloride, mean (SD), mmol/L | 108.05 (6.33) | 109.45 (6.95) | 0.181 |
TB, mean (SD), mmol/L | 40.29 (57.13) | 41.17 (53.33) | 0.918 |
DB, mean (SD), mmol/L | 30.97 (47.86) | 33.20 (46.99) | 0.763 |
ALT, mean (SD), mmol/L | 50.06 (167.93) | 92.73 (199.87) | 0.140 |
AST, mean (SD), mmol/L | 78.55 (228.91) | 164.60 (465.49) | 0.137 |
ALB, mean (SD), mmol/L | 30.74 (5.11) | 29.41 (6.21) | 0.135 |
Glu, mean (SD), mmol/L | 10.07 (3.11) | 10.06 (3.72) | 0.982 |
Crea, mean (SD), mmol/L | 141.64 (140.04) | 212.41 (196.63) | 0.009 |
Cys-c, mean (SD), mmol/L | 1.43 (0.83) | 1.93 (1.35) | 0.005 |
GGT, mean (SD), mmol/L | 108.49 (123.97) | 91.62 (108.70) | 0.352 |
TG, mean (SD), mmol/L | 3.56 (2.26) | 4.07 (5.21) | 0.419 |