Table 2 Correlation between clinicopathological variables and ADAR expression and CNV in Gastric cancer patients
From: ADAR expression and copy number variation in patients with advanced gastric cancer
variable | ADAR expression | P value | ADAR amplification | P value | ||
|---|---|---|---|---|---|---|
High(17) | Low(25) | Yes(18) | No(24) | |||
Age (year) | ||||||
≥ 66a | 11 | 14 | 0.573 | 11 | 14 | 0.856 |
< 66 | 6 | 11 | 7 | 10 | ||
Gender | ||||||
Male | 11 | 15 | 0.758 | 12 | 14 | 0.582 |
Female | 6 | 10 | 6 | 10 | ||
Pathological N category | ||||||
N0 | 1 | 1 | 0.074 | 1 | 1 | 0.086 |
N1 | 1 | 4 | 0 | 5 | ||
N2 | 5 | 15 | 8 | 12 | ||
N3 | 10 | 5 | 9 | 6 | ||
M classification | ||||||
M0 | 6 | 19 | 0.008* | 7 | 18 | 0.018* |
M1 | 11 | 6 | 11 | 6 | ||
Site of primary tumor | ||||||
Antrum | 4 | 6 | 0.937 | 4 | 6 | 0.315 |
Body | 8 | 13 | 9 | 12 | ||
Cardia | 4 | 4 | 5 | 3 | ||
Fundus | 1 | 2 | 0 | 3 | ||
Histology | ||||||
Well differentiated | 0 | 5 | 0.015* | 1 | 4 | 0.143 |
Moderately differentiated | 3 | 11 | 4 | 10 | ||
Poorly differentiated | 10 | 8 | 9 | 9 | ||
Undifferentiated | 4 | 1 | 4 | 1 | ||
Size of primary tumor | ||||||
< 6.1 | 7 | 21 | 0.004* | 8 | 20 | 0.008* |
≥ 6.1 | 10 | 4 | 10 | 4 | ||
Tumor stage | ||||||
Stage 4 | 11 | 6 | 0.008* | 11 | 6 | 0.018* |
Stage 3 | 6 | 19 | 7 | 18 | ||
Lymphovascular invasion | ||||||
Present | 14 | 16 | 0.196 | 15 | 15 | 0.139 |
Absent | 3 | 9 | 3 | 9 | ||