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Table 2 UC therapeutic strategies, disease course and complications

From: Elderly-onset vs adult-onset ulcerative colitis: a different natural history?

 

Elderly (≥ 65 yrs)

N = 94

Adults (40–64 yrs)

N = 94

p value

Therapy at the diagnosis

 Mesalamine N (yrs, SD)

55 (58.5)

51 (54.8)

0.612

 Steroids N (%)

36 (38.3)

31 (33.3)

0.479

 Surgery at the diagnosis (%)

5 (5.3)

3 (3.2)

0.479

Follow-up

 Surgery N (%)

19 (20.4)

8 (8.5)

0.020

 Months to surgery, mean (SD)

18.4 (34.1)

24,87 (23.9)

0.2903

 Mesalamine N (%)

90 (95.7)

86 (96.7)

0.351

 Immunosuppressant N (%)

10 (10.8)

11 (12.1)

0.837

 Biological therapy N (%)

2 (2.1)

20 (22)

< 0.0005

 Patients with one relapse or more, N (%)

54 (57.5)

52 (57.1)

0.932

 Time to first relapse in months, mean (SD)

19.04 (28.6)

16,49 (22.9)

0.5615

 Extraintestinal manifestations N(%)

9 (9.6)

18 (19.2)

0.061

Complications

 Intestinal complications N (%)

17 (18.1)

5 (5.5)

0.0007

 Systemic infections, N (%)

28 (29.8)

24 (25.5)

0.514