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Table 1 Clinicopathological characteristics of considered PDAC, PanNET and AVC

From: Exosomal miRNA signatures of pancreatic lesions

Variable

PDAC (n = 55)

PanNET (n = 42)

AVC (n = 19)b

Gender

 F

22 (40%)

16 (38%)

10 (53%)

 M

33 (60%)

26 (62%)

9 (47%)

 Age (years)

64.5 ± 10,5

51.1 ± 13.65

63.4 ± 11.18

(median 67.0)

(median 49.5)

(median 63)

Primary tumor

 T1

5 (9%)

20 (47%)

3 (15%)

 T2

25 (46%)

15 (36%)

6 (30%)

 T3

9 (16%)

7 (17%)

9 (45%)

 T4

6 (11%)

0 (0%)

0 (0%)

an.a.

10 (18%)

0 (0%)

1 (5%)

Regional lymph nodes

 N0

3 (6%)

22 (52%)

7 (35%)

 N1

15 (27%)

12 (29%)

7 (35%)

 N2

21 (38%)

0 (0%)

4 (20%)

 n.a.

16 (29%)

8 (19%)

1 (5%)

Distant metastasis

 M0

38 (69%)

40 (95%)

18 (90%)

 M1

11 (20%)

2 (5%)

1 (10%)

 n.a.

6 (11%)

0 (0%)

0 (0%)

Clinical stage

 I

3 (6%)

11 (26%)

6 (30%)

 II

15 (27%)

11 (26%)

0 (0%)

 III

20 (36%)

10 (24%)

12 (60%)

 IV

11 (20%)

2 (5%)

1 (5%)

 n.a.

6 (11%)

8 (19%)

0 (0%)

Grade

 G1

0 (0%)

29 (69%)

2 (10%)

 G2

25 (45.5%)

13 (31%)

12 (60%)

 G3

14 (25.5%)

0 (0%)

4 (20%)

 n.a.

16 (29%)

0 (0%)

1 (5%)

Lymphovascular invasion

 absent

1 (2%)

17 (40.5%)

3 (15%)

 present

38 (69%)

17 (40.5%)

15 (75%)

 n.a.

16 (29%)

8 (19%)

1 (5%)

Perineural invasion

 absent

0 (0%)

22 (52%)

5 (25%)

 present

39 (71%)

12 (29%)

13 (65%)

 n.a.

16 (29%)

8 (19%)

1 (5%)

  1. an.a (not available data): patients who did not undergo radical surgery; bOne out of 20 AVCs is represented by an adenomatous lesion with high-grade dysplasia (this case has not been reported in the table)