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Table 1 Reported cases of colorectal cancer metastasis to thyroid neoplasm in the literature

From: Metastatic rectal cancer to papillary thyroid carcinoma: a case report and review of literature

Author and publish year

Age (year)/gender

Primary site

History with thyroid

Clinical symptoms of thyroid tumor

FNA diagnosis

Thyroid tumor

CEA level (ng/ml)

Interval from primary cancer diagnosis

Metastatic Organs

Treatment of thyroid tumor

Prognosis after thyroid tumor diagnosis

Kameyama 2000 [3]

82/M

sigmoid colon

NA

Autopsy

NA

Microfollicular adenoma

217

2 years

Multiple organs

None

Dead

Witt 2003 [4]

71/M

colon

a long-standing thyroid goite

Thyroid mass, airway obstruction

Benign thyroid goiter

Hürtle cell carcinoma

NA

7 years

Thyroid

Thyroidectomy

NA

Fadare 2005 [5]

59/F

sigmoid colon

a thyroid nodule 23 years

Enlarged left thyroid lobe

Follicular neoplasm

Follicular adenoma

NA

Synchronous

Liver and thyroid

Subtotal left thyroidectomy

>2 years

Cherk 2008 [6]

52/M

rectal

NA

Asymptomatic+ PET/CT

PTC

PTC

9.7

18 months

Lung and thyroid

Right hemi-thyroidectomy

NA

Jin 2014 [7]

62/F

rectal

goiter over 50 years

Goiter, dyspnea

NA

PTC

22.68

21 months

Thyroid

Partial thyroidectomy

>2 years

Yeo 2014 [8]

53/M

sigmoid colon

NA

Asymptomatic + PET/CT + ultrasound

MTC

MTC

17.3

2 years

Lung and thyroid

Total thyroidectomy and bilateral central neck dissection

1 year

Amenduni 2014 [9]

63/F

left side colon

NA

Cervical swelling, dyspnoea

NA

Papillary microcarcinoma

NA

2 years

Thyroid

Total thyroidectomy

NA

Melis 2018 [10]

53/M

colon

NA

Asymptomatic+ MRI

Follicular neoplasm + mCRC

Follicular carcinoma

NA

9 years

Thyroid

Thyroidectomy

>1 year

Current case 2019

34/F

rectal

NA

Cervical bump, neck pain and hoarseness

PTC

PTC

19

6 years

Lung and thyroid

Total thyroidectomy and bilateral cervical dissection

>1 year

  1. Note: NA Not available or not clearly stated, MTC Medullary thyroid carcinoma, PTC Papillary thyroid carcinoma, mCRC Metastasis colorectal cancer