Variable | All patients (n = 329) | Normal lactate (n = 112) | Elevated lactate (n = 217) | P value |
---|---|---|---|---|
Age, years, (SD) | 51.4 ± 13.8 | 51.8 ± 13.2 | 51.2 ± 14.2 | 0.71 |
Sex (male), n (%) | 194 (59%) | 66 (59%) | 128 (59%) | 0.74 |
Etiology, n (%) | 0.06 | |||
Biliary | 161 (49%) | 65 (58%) | 96 (44%) | |
Alcoholic | 42 (13%) | 15 (13%) | 27 (12%) | |
Hyperlipidemia | 102 (31%) | 27 (24%) | 75 (35%) | |
Other | 24 (7%) | 5 (5%) | 19 (9%) | |
Body-mass index, Kg/m2, (SD) | 24.6 ± 3.7 | 24.2 ± 3.7 | 24.5 ± 3.7 | 0.82 |
Balthazar grading standard, n (%) | 0.13 | |||
C- grade | 26 (8%) | 13 (12%) | 13 (6%) | |
D- grade | 222 (67%) | 76 (68%) | 146 (67%) | |
E- grade | 81 (25%) | 23 (20%) | 58 (27%) | |
Laboratory data | ||||
White blood count, × 109/L, (SD) | 14.3 ± 6.8 | 15.2 ± 5.4 | 14.9 ± 6.3 | 0.23 |
Hematocrit, IQR | 43.1 (38.9–48.9) | 41 (36.6–46.1) | 44.4 (40–50) | < 0.01 |
Hematocrit ≥44, n (%) | 154 (47%) | 35 (31%) | 119 (59%) | < 0.01 |
Serum calcium, mmol/L, | 1.9 (1.7–2.1) | 2 (1.8–2.2) | 1.9 (1.6–2.1) | 0.01 |
Serum calcium< 2 mmol/L, n (%) | 182 (55%) | 50 (45%) | 132 (61%) | 0.06 |
Serum glucose, mmol/L, IQR | 9.3 (7.3–12.7) | 7.7 (6.1–9.7) | 10.5 (8.0–14.7) | < 0.01 |
Serum urea, mmol/L, IQR | 7.3 (5.0–11.5) | 5.7 (4.1–9.6) | 7.7 (5.6–12.4) | < 0.01 |
Serum creatinine≥1.9 mg / dl, n (%) | 74 (22%) | 10 (9%) | 64 (29%) | < 0.01 |
Serum albumin | 35 ± 5.4 | 35.4 ± 5.3 | 34.8 ± 5.4 | 0.37 |
C-reactive protein ≥150 mg/L, n (%) | 269 (82%) | 90 (80%) | 179 (82%) | 0.64 |
Procalcitonin≥3.8 ng/mL, n (%) | 142 (43%) | 23 (21%) | 119 (55%) | < 0.01 |
BE ≥|4|mmol/L, n (%) | 170 (52%) | 30 (27%) | 140 (65%) | < 0.01 |
Severity scores | ||||
SIRS scores ≥3, n (%) | 128 (39%) | 36 (32%) | 92 (42%) | 0.07 |
APACHEIIscores, IQR | 10 (7–13) | 9 (7–12) | 11 (8–14) | < 0.01 |
APACHEIIscores≥15, n (%) | 68 (18%) | 13 (12%) | 55 (25%) | < 0.01 |