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Table 3 Logistic regression analysis to identify potential factors associated with EOT HBsAg level ≤ 10 IU/mL

From: HBsAg quantification predicts off-treatment response to interferon in chronic hepatitis B patients: a retrospective study of 250 cases

Variables

HR

95% CI

p-value

Male

0.605

0.184–1.985

0.407

Over 30 years old

0.664

0.179–2.458

0.540

Baseline ALT > 4 × ULN U/L

17.241

1.689–166.667

0.016

Baseline HBV DNA < 2 × 106 IU/mL

7.813

1.961–31.250

0.004

Baseline HBsAg < 25,000 IU/mL

1.624

1.083–2.435

0.019

On-treatment HBsAg decline > 1 log10IU/mL at week 24

55.556

11.904–250

< 0.001

On-treatment HBV DNA decline > 2 log10IU/mL at week 24

14.084

3.003–66.667

0.001

Duration of IFN over 1 year

2.140

0.680–6.736

0.193

  1. ALT alanine aminotransferase, ULN upper limit of normal, IFN interferon. P-values < 0.05 are shown in bold italics