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Table 2 Plasma levels of complement components in the HBV-ACLF, CHB group and health control groups

From: Lower level of complement component C3 and C3a in the plasma means poor outcome in the patients with hepatitis B virus related acute-on-chronic liver failure

Characteristics

Control group

CHB group

ACLF group

P Value

C1q (ng/ml)

177,001 (145157–214,153)

114,640 (34586–198,231)

50,509 (16011–113,313)

< 0.0001

MBL (ng/ml)

3788 (1894–4590)

3785 (2716–4666)

3768 (2402–4749)

0.9571

FB (ng/ml)

236.5 (147.8–303.8)

214.3 (176.0–270.6)

222.4 (141.8–267.4)

0.7615

C3 (μg/ml)

15,653 (12550–16,220)

8916 (3598–16,893)

6568 (1188–15,387)

< 0.0001

C3a (ng/ml)

1755 (1159–1961)

1008 (894–1654)

852 (714–1740)

< 0.0001

C4 (μg/ml)

1530 (498–1843)

1487 (76–2006)

1074 (49–1554)

0.0054

C4a (ng/ml)

2398 (1086–3013)

2304 (1575–3007)

1811 (417–2757)

0.0003

sC5b-9 (ng/ml)

784 (445–2626)

396 (121–2288)

130 (79–1772)

0.0115

  1. Continuous variables were presented as median and the range was shown in brackets