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Table 3 Difference of characteristics between the study subgroups

From: Prostaglandin E-major urinary metabolite versus fecal immunochemical occult blood test as a biomarker for patient with ulcerative colitis

Characteristics

Disease duration

P value

<  5 years, n = 48

≥ 5 years, n = 44

Age (year), mean ± SD

46.6 ± 15.2

50.7 ± 17.8

0.232

Male/Female, n (%)

33 / 15 (68.8/31.2)

31/13 (70.5/29.5)

 

Disease duration (year), mean ± SD

2.1 ± 1.3

12.7 ± 6.5

<  0.001

Disease extent, n (%)

 Extensive colitis

31 (64.6)

26 (59.1)

 

 Left sided colitis

8 (16.7)

16 (36.4)

 

 Proctitis

9 (18.7)

2 (4.5)

 

CAI (Lichtiger’s socre) mean ± SD

2.5 ± 2.9

1.3 ± 1.7

0.016

eMayo mean ± SD

1.1 ± 1.0

0.9 ± 1.0

0.250

 eMayo 0, n (%)

16 (33.3)

22 (50.0)

 

 eMayo 1, n (%)

13 (27.1)

8 (18.2)

 

 eMayo 2, n (%)

16 (33.3)

11 (25.0)

 

 eMayo 3, n (%)

3 (6.2)

3 (6.8)

 

UCEIS score mean ± SD

2.4 ± 1.9

1.8 ± 1.9

0.146

PGE-MUM (μ•g−1•Cr− 1) mean ± SD

32.3 ± 16.8

25.8 ± 19.5

0.088

FIT (ng/ml), n (%) mean ± SD

3285.8 ± 5953.5

969.6 ± 2118.1

0.017

Medication at study, n (%)

 Oral 5-ASA

25 (52.1)

33 (75)

 

 Suppository 5-ASA

10 (20.8)

7 (15.9)

 

 Systemic steroids

9 (18.8)

3 (6.8)

 

 Azathioprine/Mercaptopurine

22 (45.8)

13 (29.5)

 

 Tacrolimus

7 (14.6)

3 (6.8)

 

 Biologics

13 (27.1)

12 (27.3)

 
  1. CAI clinical activity index, eMayo Mayo endoscopic subscore, UCEIS Ulcerative Colitis Endoscopic Index of Severity, PGE-MUM Prostaglandin E-Major Urinary Metabolite, FIT fecal immunochemical occult blood test, 5-ASA 5-aminosalicylic acid