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Table 1 Comparison of demographics and clinical characteristics between the HTBA group and the NTBA group

From: Increased circulating total bile acid levels were associated with organ failure in patients with acute pancreatitis

 

D1

D2

D3

Variable

NTBA

HTBA

Pvalue

NTBA

HTBA

Pvalue

NTBA

HTBA

Pvalue

n= 262

n= 17

n= 269

n= 22

n= 262

n=31

Demographics

 Age, yr, mean±SD

46.7±12.6

48.5±12.2

0.56

46.9±12.5

48.0±13.4

0.699

46.8±12.5

48.5±13.0

0.469

 Male, n(%)

162(61.8)

15(88.2)

0.028

169(62.8)

20(90.9)

0.008

163(62.2)

28(90.3)

0.002

 BMI, n(%)

  

0.026

  

0.035

  

0.264

  <28

173(77.9)

8(50.0)

 

179(78.5)

11(55.0)

 

171(77.4)

19(67.9)

 

  ≥28

49(22.1)

8(50.0)

 

49(21.5)

9(45.0)

 

50(22.6)

9(32.1)

 

 Etiology of SAP, n(%)

  

0.306

  

0.327

  

0.357

  Biliary

126(48.1)

12(70.6)

 

131(48.7)

15(68.2)

 

127(48.5)

20(64.5)

 

  Hyperlipidemia

110(42.0)

4(23.5)

 

111(41.3)

6(27.3)

 

110(42.0)

8(25.8)

 

  Alcoholic

10(3.8)

0(0)

 

10(3.7)

0(0)

 

9(3.4)

1(3.2)

 

  Idiopathic

16(6.1)

1(5.9)

 

17(6.3)

1(4.5)

 

16(6.1)

2(6.5)

 

Comorbidities, n(%)

 Hypertension

70(26.7)

8(47.1)

0.125

74(27.5)

9(40.9)

0.181

70(26.7)

13(41.9)

0.075

 DM

64(24.4)

3(17.6)

0.733

66(24.5)

3(13.6)

0.248

63(24.0)

6(19.4)

0.561

 Biliary tract disease

129(49.2)

10(58.8)

0.444

133(49.4)

11(50.0)

0.96

131(50.0)

14(45.2)

0.61

 Fatty liver

115(43.9)

6(35.3)

0.488

118(43.9)

9(40.9)

0.788

117(44.7)

12(38.7)

0.528

Smoking, n(%)

106(40.5)

9(52.9)

0.311

111(41.3)

12(54.5)

0.225

106(40.5)

18(58.1)

0.061

Drinking, n(%)

83(31.7)

8(47.1)

0.19

88(32.7)

12(54.5)

0.038

83(31.7)

18(58.1)

0.003

 

D5

D7

   

Variable

NTBA

HTBA

Pvalue

NTBA

HTBA

Pvalue

   

n= 251

n= 42

n= 239

n= 54

   

Demographics

 Age, yr, mean±SD

46.9±12.7

47.3±11.6

0.865

46.7±12.6

48.3±12.2

0.382

   

 Male, n(%)

153(61.0)

38(90.5)

<0.001

143(59.8)

48(88.9)

<0.001

   

 BMI, n(%)

 

0.098

 

0.141

   

  <28

165(78.2)

25(65.8)

 

158(78.2)

32(68.1)

    

  ≥28

46(21.8)

13(34.2)

 

44(21.8)

15(31.9)

    

 Etiology of SAP, n(%)

 

0.769

 

0.674

   

  Biliary

124(49.4)

23(54.8)

 

116(48.5)

31(57.4)

    

  Hyperlipidemia

104(41.4)

14(33.3)

 

100(41.8)

18(33.3)

    

  Alcoholic

8(3.2)

2(4.8)

 

8(3.3)

2(3.7)

    

  Idiopathic

15(6.0)

3(7.1)

 

15(6.3)

3(5.6)

    

Comorbidities, n(%)

 Hypertension

67(26.7)

16(38.1)

0.129

62(25.9)

21(38.9)

0.057

   

 DM

62(24.7)

7(16.7)

0.256

58(24.3)

11(20.4)

0.542

   

 Biliary tract disease

128(51.0)

17(40.5)

0.207

120(50.2)

25(46.3)

0.603

   

 Fatty liver

109(43.4)

20(47.6)

0.612

106(44.4)

23(42.6)

0.814

   

Smoking, n(%)

98(39.0)

26(61.9)

0.006

92(38.5)

32(59.3)

0.005

   

Drinking, n(%)

77(30.7)

24(57.1)

0.001

69(28.9)

32(59.3)

<0.001

   
  1. HTBA The high TBA group, NTBA The normal TBA group, SD Standard deviation, BMI Body mass index, SAP Severe acute pancreatitis, DM Diabetes mellitus