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Table 3 Univariate analysis and multivariate analysis for predictors of advanced fibrosis in the elderly and non-elderly patients with NAFLD

From: Predictors of advanced fibrosis in elderly patients with biopsy-confirmed nonalcoholic fatty liver disease: the GOASIA study

Characteristics

Elderly NAFLD patients

Non-elderly NAFLD patients

Univariate analysis

Multivariate analysis

Univariate analysis

Multivariate analysis

OR (95%CI)

P-value

OR (95%CI)

P-value

OR (95%CI)

P-value

OR (95%CI)

P-value

Age > 70 years

2.22 (0.85–5.80)

0.103

2.24 (0.43–11.61)

0.338

    

Female

2.60 (1.33–5.08)

0.005

3.21 (1.37–7.54)

0.007

0.89 (0.53–1.47)

0.639

0.59 (0.3–1.15)

0.119

BMI > 25 kg/m2

2.74 (1.25–6.00)

0.011

2.41 (0.85–6.8)

0.098

1.13 (0.55–2.31)

0.741

0.94 (0.35–2.54)

0.904

Central obesity

4.75 (1.34–16.88)

0.016

4.09 (0.68–24.67)

0.124

1.24 (0.53–2.88)

0.62

1.18 (0.44–3.18)

0.747

Diabetes mellitus

2.07 (1.00–4.26)

0.049

2.29 (0.88–5.93)

0.088

3.88 (2.22–6.79)

< 0.001

3.38 (1.7–6.73)

0.001

Hypertension

3.73 (1.53–9.07)

0.004

3.68 (1.11–12.23)

0.034

1.29 (0.76–2.21)

0.346

1.59 (0.8–3.12

0.183

Dyslipidemia

1.36 (0.56–3.33)

0.494

  

1.01 (0.58–1.76)

0.97

  

Platelet count < 140 × 109/L

2.73 (1.12–6.67)

0.027

2.43 (0.59–9.91)

0.217

4.06 (1.85–8.88)

< 0.001

4.18 (1.32–13.25)

0.015

  1. OR odd ratios, CI confidence intervals
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BMC Gastroenterology

ISSN: 1471-230X

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