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Table 3 Univariate analysis of the study parameters that had a positive role for liver fibrosis. Only those that achieved statistical significance are presented

From: Causative factors of liver fibrosis in HIV-infected patients. A single center study

Parameter

Effect estimate a

95% CI

P value

Age (years)

0.023

0.0018–0.067

0.0285

AST (IU/ml)

0.083

0.020–0.17

0.0003

ALT (IU/ml)

0.034

0.0005–0.114

0.0081

γGT (IU/ml)

0.051

0.0057–0.13

0.0012

LRE (Yes vs. No)

4.6

1.5–14.3

0.0051

Number of LREs

0.038

0.0007–0.114

0.0052

Events of transaminasemia

0.060

0.0043–0.16

0.0042

HCV co-infection (Yes vs. No)

4.2

1.2–15.1

0.0178

Alcohol overuse (Yes vs. No)

3.9

1.1–13.9

0.0244

Diabetes Mellitus (Yes vs. No)

5.6

1.0–31.9

0.0307

Clinical AIDS (Stage CDC – C vs. non C)

4.4

1.4–13.4

0.0055

  1. AST Aspartate Aminotransferase, ALT Alanine Aminotransferase γ-GT: Gamma Glutamyl Transpeptidase, LRE Liver related event, HCV Hepatitis C, AIDS Acquired Immune Deficiency Syndrome.
  2. a Effect is reported as epsilon-square (ε2) and odds ratio for the arithmetic and categorical quantities respectively