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Table 3 Ability to predict mucosal inflammation (MES 1 or 2 or 3) with optimal cutoff value by ROC curve

From: Serum amyloid A is a better predictive biomarker of mucosal healing than C-reactive protein in ulcerative colitis in clinical remission

 

CRP

SAA

Sensitivity (95% CI)

0.557 (0.461–0.649)

0.574 (0.478–0.666)

Specificity (95% CI)

0.702 (0.593–0.797)

0.893 (0.806–0.950)

PPV (95% CI)

0.719 (0.614–0.809)

0.880 (0.784–0.944)

NPV (95% CI)

0.536 (0.439–0.632)

0.605 (0.513–0.691)

Accuracy (95% CI)

0.618 (0.547–0.686)

0.709 (0.640–0.771)

  1. CI Confidence interval, CRP C-reactive protein, MES Mayo Endoscopic Score, NPV Negative predictive interval, PPV Positive predictive value, SAA Serum amyloid A