Table 13 Comparison of short-term effects between the irinotecan dose reduction group and non-dose reduction group
Effect | UGT1A1*28 | p | UGT1A1*6 | p | ||
|---|---|---|---|---|---|---|
Dose reduction | Non-dose reduction | Dose reduction | Non-dose reduction | |||
PR | 2 (13.3) | 11 (15.5) | 0.378 | 4 (26.7) | 9 (12.7) | 0.388 |
SD | 9 (60.0) | 29 (40.8) | 6 (40.0) | 33 (46.5) | ||
PD | 4 (26.7) | 31 (43.7) | 5 (33.3) | 29 (40.8) | ||