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Table 4 Univariate and multivariate analysis of overall survival in PDAC patients with T2DM

From: Reduced mean platelet volume levels predict shorter survival in patients with resectable pancreatic ductal adenocarcinoma and type 2 diabetes

VariablesUnivariate analysisMultivariate analysis
HR (95% CI)P-valueHR (95% CI)P-value
Age (years) (>  60 versus ≤60)1.099 (0.826–1.462)0.519  
Gender (Male versus Female)1.289 (0.963–1.725)0.0871.083 (0.795–1.476)0.614
BMI (kg/m2)0.973 (0.927–1.022)0.278  
Smoking status (Yes versus No)1.052 (0.770–1.436)0.750  
Drinking status (Yes versus No)1.076 (0.766–1.513)0.672  
FPG (mmol/L) (log-value)1.165 (0.792–1.713)0.439  
Albumin (g/L)1.013 (0.989–1.037)0.283  
Hemoglobin (g/dl)0.998 (0.989–1.008)0.706  
WBC (×109/L)1.053 (1.002–1.106)0.0431.032 (0.979–1.087)0.241
Platelet count (× 109/L)1.000 (0.999–1.002)0.629  
MPV (fL) (≤ 10.0 versus > 10.0)1.914 (1.414–2.592)<  0.0011.801 (1.305–2.485)<  0.001
CA19–9 (IU/mL)
 (≤ 37 versus > 37)1.205 (0.903–1.609)0.2051.856 (1.122–3.070)0.016
Tumor location
 (Head versus Body, tail)1.053 (0.779–1.424)0.736  
Tumor differentiation
 (Poor versus Well/ moderate)2.014 (1.473–2.753)<  0.0011.180 (0.673–2.070)0.563
Tumor size (cm)
 (>  4 versus ≤4)1.460 (1.091–1.955)0.0111.385 (0.832–2.303)0.210
Regional lymph node metastasis
 (N1 + N2 versus N0)1.481 (1.105–1.983)0.0091.268 (0.944–1.704)0.115
Chemotherapy (Yes versus No)0.166 (0.119–0.232)<  0.0010.183 (0.128–0.261)<  0.001
  1. Abbreviations: see to Table 1