Table 1 The clinicopathological features among PDAC patients in relation to T2DM status
Variables | With T2DM | Without T2DM | P value |
|---|---|---|---|
N | 202 | 601 | |
Age (years) | 61.7 (8.7) | 58.2 (10.9) | < 0.001 |
Sex (male, %) | 120 (59.4) | 367 (61.1) | 0.676 |
BMI (kg/m2) | 23.4 (3.2) | 23.1 (3.3) | 0.183 |
Smoker (n, %) | 61 (30.2) | 206 (34.3) | 0.287 |
Drinking (n, %) | 44 (21.8) | 113 (18.8) | 0.356 |
FPG (mmol/L) | 8.45 (6.70–11.10) | 5.40 (4.95–6.10) | < 0.001 |
Albumin (g/L) | 40.4 (6.7) | 40.1 (6.4) | 0.599 |
WBC (×109/L) | 7.38 (3.19) | 6.72 (2.77) | 0.005 |
Hemoglobin (g/dl) | 129.0 (15.2) | 129.9 (17.7) | 0.512 |
Platelet count (×109/L) | 216.6 (87.2) | 223.6 (78.0) | 0.278 |
MPV (fL) | 9.9 (1.9) | 10.3 (2.0) | 0.011 |
CA19–9 (IU/mL) | 0.577 | ||
≤ 37 | 38 (18.8) | 124 (20.6) | |
> 37 | 164 (81.2) | 477 (79.4) | |
Tumor location | 0.240 | ||
Head | 135 (66.8) | 374 (62.2) | |
Body, tail | 67 (33.2) | 227 (37.8) | |
Tumor differentiation | 0.092 | ||
Well/moderate | 170 (84.2) | 533 (88.7) | |
Poor | 32 (15.8) | 68 (11.3) | |
Tumor size (cm) | 0.156 | ||
≤ 4 | 158 (78.2) | 497 (82.7) | |
> 4 | 44 (21.8) | 104 (17.3) | |
Regional lymph node metastasis | < 0.001 | ||
N0 | 124 (61.4) | 464 (77.2) | |
N1 | 69 (34.2) | 111 (18.5) | |
N2 | 9 (4.5) | 26 (4.3) | |
Postoperative adjuvant chemotherapy | 0.334 | ||
Yes | 103 (51.0) | 330 (54.9) | |
No | 99 (49.0) | 271 (45.1) |