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Table 7 Hazard ratio for unfavourable events for each MPR cut off threshold, and interpretation of risk reduction of unfavourable events, using alternate classifications presented in Table 6 in Appendix (sensitivity analysis)

From: Adherence in chronic hepatitis B: associations between medication possession ratio and adverse viral outcomes

MPR category

Number of individuals in category

Number of individuals with unfavourable outcomes

Hazard ratio for unfavourable events with MPR above threshold (95% CI) p-value

Interpretation of risk reduction of unfavourable events with MPR above threshold

< 0.80

97

11

0.08 (0.03–0.21) < 0.001

92%

< 0.90

137

12

0.11 (0.04, 0.30) < 0.001

89%

< 0.95

197

13

0.16 (0.05, 0.45) 0.001

84%

< 1.00

346

16

0.26 (0.07, 0.91) 0.034

74%

< 1.05

510

18

0.31 (0.04, 2.33) 0.254

No evidence of association