The propionic acid and butyric acid in serum but not in feces are increased in patients with diarrhea-predominant irritable bowel syndrome

Table 2 Propionate and butyrate in serum in patients with IBS-D and HCs

SCFAs in serum (mmol/L)	IBS-D (n = 21)	HCs(n = 14)	t value	P value
propionate	2.96 ± 0.16	2.843 ± 0.10	−2.65	0.01
butyrate	2.80 ± 0.13	2.70 ± 0.08	−2.67	0.01
Propionate –Butyrate	0.16 ± 0.23	0.15 ± 0.10	−0.21	0.84
Propionate/Butyrate	1.06 ± 0.08	1.05 ± 0.04	−0.22	0.83

T-test was adopted in group measurement data. SCFAS, short-chain fatty acids; IBS-D, diarrhea-predominant IBS; HC, healthy control

ISSN: 1471-230X