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Table 2 Propionate and butyrate in serum in patients with IBS-D and HCs

From: The propionic acid and butyric acid in serum but not in feces are increased in patients with diarrhea-predominant irritable bowel syndrome

SCFAs in serum (mmol/L)IBS-D (n = 21)HCs(n = 14)t valueP value
propionate2.96 ± 0.162.843 ± 0.10−2.650.01
butyrate2.80 ± 0.132.70 ± 0.08−2.670.01
Propionate –Butyrate0.16 ± 0.230.15 ± 0.10−0.210.84
Propionate/Butyrate1.06 ± 0.081.05 ± 0.04−0.220.83
  1. T-test was adopted in group measurement data. SCFAS, short-chain fatty acids; IBS-D, diarrhea-predominant IBS; HC, healthy control