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Table 1 Faecal SCFAs in patients with IBS-D and HCs with comparisons between the groups

From: The propionic acid and butyric acid in serum but not in feces are increased in patients with diarrhea-predominant irritable bowel syndrome

SCFAs (mg/g)

IBS-D (n = 21)

HC(n = 14)

t value

P value

Acetate

4.95 ± 1.07

4.77 ± 1.47

−0.42

0.68

Propionate

6.34 ± 1.01

6.28 ± 1.08

−0.17

0.87

Butyrate

2.98 ± 0.51

3.07 ± 0.45

0.55

0.61

Propionate –Butyrate

3.36 ± 1.10

3.21 ± 1.05

−0.40

0.69

Propionate/Butyrate

2.18 ± 0.50

2.08 ± 0.42

−0.67

0.51

  1. T-test was adopted in group measurement data. SCFAS, short-chain fatty acids; IBS-D, diarrhea-predominant IBS; HC, healthy control