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Table 6 Patient-based coverage of blood culture pathogens

From: Use of microbiological and patient data for choice of empirical antibiotic therapy in acute cholangitis

Risc factor

  

CTX

TZP

CP

  

n

 

p-value

 

p-value

 

p-value

Time of bile collection from admission

≤ 48 h

21

71.4%

0.062

81.0%

0.044

95.2%

0.101

>  48 h

23

43.5%

52.2%

78.3%

ICU

no

29

69.0%

0.024

75.9%

0.053

89.7%

0.376

yes

15

33.3%

46.7%

80.0%

Indwelling biliary tract drainage

no

22

68.2%

0.128

81.8%

0.026

90.9%

0.380

yes

22

45.5%

50.0%

81.8%

Any of the above risk factors

no

9

77.8%

0.155

100.0%

0.016

100.0%

0.181

yes

35

51.4%

57.1%

82.9%

  1. Percentages indicate the proportion of patients for whom all blood culture pathogens would have been covered by the respective antibiotic
  2. CTX cefotaxime, TZP piperacillin/tazobactam, CP carbapenem
  3. ICU, treatment on ICU before or during bile sampling