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Table 3 Patient characterisitics

From: Use of microbiological and patient data for choice of empirical antibiotic therapy in acute cholangitis

Total study populationN = 348 
  (n) 
Male63.8%222 
 medianmin./max. 
Age at intervention (years)6418/94 
Age-adjusted Charlson index50/12 
 Cardiovascular disease42.2%147 
 Malignoma40.5%141 
 Liver disease27.6%96 
 Diabetes24.1%84 
 Kidney disease20.4%71 
 Pulmonary disease15.2%53 
 Neurologic disorder8.6%30 
MDR colonization15.6%59 
Preexisting biliary tract pathologiesa83.0%289 
 Papillotomy30.7%107 
 Malignant stenosis30.5%106 
 Biliodigestive anastomosis28.7%100 
 Choledocholithiasis23.9%83 
 Benign stenosis23.6%82 
 Liver transplatation13.2%46 
Prior biliary tract interventions
 Yes81.0%282 
 No18.4%64 
 N.d.0.6%2 
 medianmin./max. 
 Number of prior interventionsb20/32 
Preexisting biliary tract drainage
 Yes58.9%205 
 No41.1%143 
 N.d.8.0%28 
Antibiotic pre-treatment within 90 d
 Yes46.6%162 
 No45.4%158 
 N.d.8.0%28 
Indication for recent intervention
 Stenosis25.9%90 
 Choledocholithiasis21.0%73 
 Catheter related14.4%50 
 Drainage after LTX8.0%28 
 Liver abscess4.9%17 
 Pancreatitis4.6%16 
 Other21.3%74 
Route of biliary drainage
 Endoscopic58.3%203 
 Percutaneous40.5%141 
 N.d.1.1%4 
Successful biliary decompression
 Yes92.8%323 
 No3.4%12 
 N.d.3.7%13 
Outcome
 Death14.4%50 
 Admission to ICU37.6%131 
 median  
 Length of hospital stay (days)16.51/367 
  1. N.d., not determinable/not documented
  2. MDR, multi-drug resistant bacteria including MRSA, MRGN, and VRE
  3. aOne or more underlying conditions possible in one individual
  4. b The exact number of prior biliary tract interventions was known in 260 cases