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Table 3 Patient characterisitics

From: Use of microbiological and patient data for choice of empirical antibiotic therapy in acute cholangitis

Total study population

N = 348

 
  

(n)

 

Male

63.8%

222

 
 

median

min./max.

 

Age at intervention (years)

64

18/94

 

Age-adjusted Charlson index

5

0/12

 

 Cardiovascular disease

42.2%

147

 

 Malignoma

40.5%

141

 

 Liver disease

27.6%

96

 

 Diabetes

24.1%

84

 

 Kidney disease

20.4%

71

 

 Pulmonary disease

15.2%

53

 

 Neurologic disorder

8.6%

30

 

MDR colonization

15.6%

59

 

Preexisting biliary tract pathologiesa

83.0%

289

 

 Papillotomy

30.7%

107

 

 Malignant stenosis

30.5%

106

 

 Biliodigestive anastomosis

28.7%

100

 

 Choledocholithiasis

23.9%

83

 

 Benign stenosis

23.6%

82

 

 Liver transplatation

13.2%

46

 

Prior biliary tract interventions

 Yes

81.0%

282

 

 No

18.4%

64

 

 N.d.

0.6%

2

 
 

median

min./max.

 

 Number of prior interventionsb

2

0/32

 

Preexisting biliary tract drainage

 Yes

58.9%

205

 

 No

41.1%

143

 

 N.d.

8.0%

28

 

Antibiotic pre-treatment within 90 d

 Yes

46.6%

162

 

 No

45.4%

158

 

 N.d.

8.0%

28

 

Indication for recent intervention

 Stenosis

25.9%

90

 

 Choledocholithiasis

21.0%

73

 

 Catheter related

14.4%

50

 

 Drainage after LTX

8.0%

28

 

 Liver abscess

4.9%

17

 

 Pancreatitis

4.6%

16

 

 Other

21.3%

74

 

Route of biliary drainage

 Endoscopic

58.3%

203

 

 Percutaneous

40.5%

141

 

 N.d.

1.1%

4

 

Successful biliary decompression

 Yes

92.8%

323

 

 No

3.4%

12

 

 N.d.

3.7%

13

 

Outcome

 Death

14.4%

50

 

 Admission to ICU

37.6%

131

 
 

median

  

 Length of hospital stay (days)

16.5

1/367

 
  1. N.d., not determinable/not documented
  2. MDR, multi-drug resistant bacteria including MRSA, MRGN, and VRE
  3. aOne or more underlying conditions possible in one individual
  4. b The exact number of prior biliary tract interventions was known in 260 cases