Irritable bowel syndrome-like symptoms and health related quality of life two years after Roux-en-Y gastric bypass - a prospective cohort study

Table 3 Changes in constipation and diarrhea symptom scores from preoperatively to 2 years after Roux-en-Y Gastric bypass (RYGB)

Group	n	Δ constipation symptom score	95% CI	p-value	n	Δ diarrhea symptom score	95% CI	p-value
All participants	174	−0.29	−0.44 to −0.14	<0.001	177	−0.40	−0.58 to −0.22	<0.001
Subgroups based on IBS status preoperatively:
With IBS	21	−0.19	−0.66 to 0.28	0.41	21	−0.38	−1.1 to 0.34	0.28
Without IBS	153	−0.31	−0.46 to −0.15	<0.001	156	−0.40	−0.58 to −0.22	<0.001
Subgroups based on IBS like symptoms 2 years after RYGB:
Never IBS or IBS-like symptoms	116	−0.16	−0.32 to 0.012	0.068	119	−0.31	−0.50 to − 0.11	0.002
New onset IBS-like symptoms	37	−0.77	−1.13 to − 0.42	<0.001	37	− 0.71	− 1.15 to − 0.27	0.002
IBS preoperatively and IBS-like symptoms at 2 year follow-up visit	14	− 0.24	− 0.75 to 0.28	0.34	14	− 0.24	− 1.3 to 0.78	0.62

All participants, and subgroups based on status of irritable bowel syndrome (IBS) are presented. Significant p-values are marked in bold
The presented delta values: Gastrointestinal Symptom Rating Scale (GSRS) at the 2 year follow-up visit - GSRS at the preoperative visit. Positive delta values indicate improved symptoms after RYGB, negative delta values indicate worsened symptoms after RYGB. The results are given as mean values with 95% confidence intervals (CI). Data were analyzed with paired t-tests
New onset IBS: no IBS preoperatively, but IBS-like symptoms 2 years after RYGB. Never IBS: No IBS preoperatively or IBS-like symptoms 2 years after RYGB
Missing data Δ constipation symptom score: All participants; n = 59. Subgroups based on IBS status preoperatively: with IBS; n = 6, without IBS; n = 53. Subgroups based on IBS-like symptoms 2 years after RYGB: never IBS or IBS-like symptoms; n = 45, new onset IBS-like symptoms; n = 8, IBS at preoperative and IBS-like symptoms 2 year follow-up visit; n = 2
Missing data Δ diarrhea symptom score: All participants; n = 56. Subgroups based on IBS status preoperatively: with IBS; n = 6, without IBS; n = 50, never IBS; n = 42. Subgroups based on IBS-like symptoms 2 years after RYGB: new onset IBS-like symptoms; n = 8, IBS at preoperative and IBS-like symptoms 2 year follow-up visit; n = 2

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