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Table 1 The change in duodenum estimated before and after the gluten challenge with the Marsh-Oberhuber classification.change in duodenum estimated before and after the gluten challenge with the Marsh-Oberhuber classification

From: Histological, immunohistochemical and mRNA gene expression responses in coeliac disease patients challenged with gluten using PAXgene fixed paraffin-embedded duodenal biopsies

Marsh class changeNumber of study subjects (%)
No change1 (7%)
Change by one classa2 (13%)
Change by two classesb8 (53%)
Change by three classesc4 (27%)
  1. aFrom M1 to M2, M2 to M3a, M3a to M3b, or M3b to M3c
  2. bFrom M1 to M3a, M3a to M3c, or M2 to M3b
  3. cFrom M1 to M3b, M2 to M3c, or M1 to M3c