Fig. 3From: Histological, immunohistochemical and mRNA gene expression responses in coeliac disease patients challenged with gluten using PAXgene fixed paraffin-embedded duodenal biopsiesComparison of mucosal morphology between formalin and PAXgene fixed specimens. Villous height, crypt depth and villous height:crypt depth ratio measurements in routine formalin-fixed biopsies and in PAXgene-fixed biopsies. The villi were significantly lower in PAXgene-fixed samples, but crypts were unaffected. There was also a trend towards lower villous height:crypt depth ratio in PAXgene-fixed samplesBack to article page