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Fig. 3 | BMC Gastroenterology

Fig. 3

From: Histological, immunohistochemical and mRNA gene expression responses in coeliac disease patients challenged with gluten using PAXgene fixed paraffin-embedded duodenal biopsies

Fig. 3

Comparison of mucosal morphology between formalin and PAXgene fixed specimens. Villous height, crypt depth and villous height:crypt depth ratio measurements in routine formalin-fixed biopsies and in PAXgene-fixed biopsies. The villi were significantly lower in PAXgene-fixed samples, but crypts were unaffected. There was also a trend towards lower villous height:crypt depth ratio in PAXgene-fixed samples

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