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Table 2 Factors Associated with the Survival of Patients with CRC

From: Prognoses of different pathological subtypes of colorectal cancer at different stages: A population-based retrospective cohort study

Covariate 5-y Overall Survival 5-y Cancer-Specific Survival
Total No. (OS, %) Logistic Analysis Total No. (CSS, %) Logistic Analysis
  Hazard Ratio (95% CI) P Value   Hazard Ratio (95% CI) P Value
Sex
 Male 161,545 (56.7) 1 [Reference]   160,455 (66.6) 1 [Reference]  
 Female 146,618 (57.6) 0.964 (0.950–0.978) < .001 145,807 (67.2) 0.973 (0.959–0.988) < .001
Age, y
  ≤ 44 y 18,591 (65.2) 1 [Reference]   18,463 (67.1) 1 [Reference]  
 45-59y 82,523 (67.1) 0.919 (0.888–0.950) < .001 82,076 (70.6) 0.849 (0.821–0.879) < .001
 60-74y 114,178 (61.8) 1.158 (1.121–1.196) < .001 113,505 (69.7) 0.887 (0.858–0.917) < .001
  ≥ 75y 92,871 (41.5) 2.641 (2.556–2.729) < .001 92,218 (60.1) 1.354 (1.310–1.400) < .001
Marital status
 Married 165,165 (62.8) 1 [Reference]   164,265 (70.8) 1 [Reference]  
 Unmarried 127,587 (49.1) 1.750 (1.724–1.776) < .001 126,716 (61.1) 1.544 (1.520–1.568) < .001
 Unknown 15,411 (61.7) 1.048 (1.013–1.084) .007 15,281 (72.1) 0.938 (0.904–0.974) < .001
 0 11,192 (80.0) 1 [Reference]   11,142 (93.6) 1 [Reference]  
 I 72,764 (77.7) 1.148 (1.093–1.206) < .001 72,462 (91.4) 1.376 (1.270–1.491) < .001
 II 78,593 (68.3) 1.857 (1.768–1.949) < .001 78,201 (81.6) 3.298 (3.050–3.565) < .001
 III 83,499 (59.4) 2.734 (2.605–2.869) < .001 83,024 (67.9) 6.914 (6.400–7.469) < .001
 IV 62,115 (10.6) 33.736 (31.998–35.568) < .001 61,433 (12.1) 106.242 (98.109–115.050) < .001
Histology
 AC 280,930 (58.0) 1 [Reference]   279,229 (67.8) 1 [Reference]  
 MAC 24,018 (50.7) 1.343 (1.308–1.379) < .001 23,849 (60.9) 1.352 (1.316–1.389) < .001
 SRCC 3215 (26.8) 3.772 (3.487–4.079) < .001 3184 (32.5) 4.373 (4.059–4.712) < .001
Grade
 Grade I 25,618 (69.4) 1 [Reference]   25,478 (81.1) 1 [Reference]  
 Grade II 197,250 (60.7) 1.468 (1.428–1.510) < .001 196,101 (70.9) 1.761 (1.704–1.820) < .001
 Grade III 46,599 (44.4) 2.840 (2.750–2.933) < .001 46,277 (52.7) 3.851 (3.714–3.994) < .001
 Grade IV 5770 (44.7) 2.806 (2.647–2.974) < .001 5741 (53.3) 3.760 (3.539–3.995) < .001
 Unknown 32,926 (46.2) 2.641 (2.552–2.733) < .001 32,665 (54.6) 3.568 (3.434–3.707) < .001