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Table 2 Factors Associated with the Survival of Patients with CRC

From: Prognoses of different pathological subtypes of colorectal cancer at different stages: A population-based retrospective cohort study

Covariate

5-y Overall Survival

5-y Cancer-Specific Survival

Total No. (OS, %)

Logistic Analysis

Total No. (CSS, %)

Logistic Analysis

 

Hazard Ratio (95% CI)

P Value

 

Hazard Ratio (95% CI)

P Value

Sex

 Male

161,545 (56.7)

1 [Reference]

 

160,455 (66.6)

1 [Reference]

 

 Female

146,618 (57.6)

0.964 (0.950–0.978)

< .001

145,807 (67.2)

0.973 (0.959–0.988)

< .001

Age, y

  ≤ 44 y

18,591 (65.2)

1 [Reference]

 

18,463 (67.1)

1 [Reference]

 

 45-59y

82,523 (67.1)

0.919 (0.888–0.950)

< .001

82,076 (70.6)

0.849 (0.821–0.879)

< .001

 60-74y

114,178 (61.8)

1.158 (1.121–1.196)

< .001

113,505 (69.7)

0.887 (0.858–0.917)

< .001

  ≥ 75y

92,871 (41.5)

2.641 (2.556–2.729)

< .001

92,218 (60.1)

1.354 (1.310–1.400)

< .001

Marital status

 Married

165,165 (62.8)

1 [Reference]

 

164,265 (70.8)

1 [Reference]

 

 Unmarried

127,587 (49.1)

1.750 (1.724–1.776)

< .001

126,716 (61.1)

1.544 (1.520–1.568)

< .001

 Unknown

15,411 (61.7)

1.048 (1.013–1.084)

.007

15,281 (72.1)

0.938 (0.904–0.974)

< .001

 0

11,192 (80.0)

1 [Reference]

 

11,142 (93.6)

1 [Reference]

 

 I

72,764 (77.7)

1.148 (1.093–1.206)

< .001

72,462 (91.4)

1.376 (1.270–1.491)

< .001

 II

78,593 (68.3)

1.857 (1.768–1.949)

< .001

78,201 (81.6)

3.298 (3.050–3.565)

< .001

 III

83,499 (59.4)

2.734 (2.605–2.869)

< .001

83,024 (67.9)

6.914 (6.400–7.469)

< .001

 IV

62,115 (10.6)

33.736 (31.998–35.568)

< .001

61,433 (12.1)

106.242 (98.109–115.050)

< .001

Histology

 AC

280,930 (58.0)

1 [Reference]

 

279,229 (67.8)

1 [Reference]

 

 MAC

24,018 (50.7)

1.343 (1.308–1.379)

< .001

23,849 (60.9)

1.352 (1.316–1.389)

< .001

 SRCC

3215 (26.8)

3.772 (3.487–4.079)

< .001

3184 (32.5)

4.373 (4.059–4.712)

< .001

Grade

 Grade I

25,618 (69.4)

1 [Reference]

 

25,478 (81.1)

1 [Reference]

 

 Grade II

197,250 (60.7)

1.468 (1.428–1.510)

< .001

196,101 (70.9)

1.761 (1.704–1.820)

< .001

 Grade III

46,599 (44.4)

2.840 (2.750–2.933)

< .001

46,277 (52.7)

3.851 (3.714–3.994)

< .001

 Grade IV

5770 (44.7)

2.806 (2.647–2.974)

< .001

5741 (53.3)

3.760 (3.539–3.995)

< .001

 Unknown

32,926 (46.2)

2.641 (2.552–2.733)

< .001

32,665 (54.6)

3.568 (3.434–3.707)

< .001