Fig. 4
From: VWF/ADAMTS13 ratio as a potential biomarker for early detection of hepatocellular carcinoma
Diagnostic accuracy of serum biomarkers for the early detection of HCC. The diagnostic accuracy of the VWF:Ag/ADAMTS13:AC ratio (Cutoff value 5.5, sensitivity 51%, specificity 95%, and AUC 0.73) is comparable with that of AFP-L3% (Cutoff value 5.7, sensitivity 54%, specificity 93%, and AUC 0.74). VWF, von Willebrand factor; VWF:Ag, VWF antigen; ADAMTS13, a disintegrin-like and metalloproteinase with thrombospondin type 1 motifs 13; ADAMTS13:AC, ADAMTS13 activity; AUC, area under the curve; AFP-L3%, Lens culinaris agglutinin-reactive alpha-fetoprotein; HCC, hepatocellular carcinoma