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Fig. 1 | BMC Gastroenterology

Fig. 1

From: VWF/ADAMTS13 ratio as a potential biomarker for early detection of hepatocellular carcinoma

Fig. 1

Comparison of serum biomarkers between cirrhotic patients with HCC and those without HCC. The AFP (a) and DCP (b) levels did not differ significantly between cirrhotic patients with and without HCC. The AFP-L3% (c), VEGF (d), VEGFR-2 (e) levels, as well as the VWF:Ag (g) and VWF:Ag/ADAMTS13:AC ratio (h), were significantly higher in cirrhotic patients with HCC than in those without HCC. The ADAMTS13:AC (f) was significantly lower in patients with HCC than in those without HCC. Asterisks indicate statistically significant differences between the indicated experimental groups (p < 0.05, p < 0.01). VWF, von Willebrand factor; VWF:Ag, VWF antigen; ADAMTS13, a disintegrin-like and metalloproteinase with thrombospondin type 1 motifs 13; ADAMTS13:AC, ADAMTS13 activity; VEGF, vascular endothelial growth factor; VEGFR-2, VEGF receptor-2; AFP, alpha-fetoprotein; AFP-L3%, Lens culinaris agglutinin-reactive AFP; DCP, des-γ-carboxy prothrombin; HCC: hepatocellular carcinoma; NS, not significant

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