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Fig. 4 | BMC Gastroenterology

Fig. 4

From: SNHG 6 promotes the progression of Colon and Rectal adenocarcinoma via miR-101-3p and Wnt/β-catenin signaling pathway

Fig. 4

miR-101-3p inhibited Wnt/β-catenin signaling by targeting β-catenin and c-Myc. a Dual-luciferase reporter assay revealed that miR-101-3p inhibited wt β-catenin 3′-UTR luciferase activity, while it had no effect on Mut β-catenin 3′-UTR luciferase activity in HEK293T cells. b Expression of β-catenin and c-Myc were determined by western blot in HCT116 and SW620 cells transfected with miR-101-3p mimics or si-SNHG6. c The cartoon of the mechanism underlying the SNHG6-miR-101-3p-β-catenin axis in human CRC. **P < 0.01

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