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Table 2 Subgroup analysis primary vs. secondary liver failure & ELS – Parameters & definitions

From: Extracorporeal liver support: trending epidemiology and mortality - a nationwide database analysis 2007–2015

“Primary liver failure group”
 Alcoholic liver disease ICD K70
 Liver failure, not elsewhere classified (includes fulminant liver failure) ICD K72
 Fibrosis and cirrhosis of the liver ICD K74
 Other diseases of the liver ICD K76
 Other diseases of the biliary tract ICD K83
 Malignant neoplasm of liver and intrahepatic bile ducts ICD C22
 Congenital malformations of the gallbladder, bile ducts and liver ICD Q44
 Disorders of mineral metabolism (includes M. Wilson, Hemochromatosis) ICD E83
 Other metabolic disorders ICD E88
 Other venous embolism and thrombosis (including Budd-Chiari-Syndrome) ICD I82
“Secondary liver failure group” – Cardiac surgery patient population
 Operative external circulation (when using the heart-lung machine) OPS 8–851
 Operations on valves and septa of the heart and cardiac vessel OPS 5–35
 Surgery on the coronary vessels OPS 5–36
 Rhythm surgery and other operations on the heart and pericardium OPS 5–37
 Resection and replacement (interposition) at the aorta OPS 5–384
  1. Primary liver failure group coding was chosen according to typical criteria by EuroTransplant for performed non-high-urgency liver transplantation (See reference [12], Jochman et al.). Secondary liver failure group (“Cardiac population”) was chosen according to predefined cardiac surgical procedures (coronary, valvular and aortic surgery performed in combination with heart-lung machine)