|
Parameters
|
Survivors (n = 30)
|
Non-survivors (n = 41)
|
P value
|
|---|
|
Age (years)
|
43.08 ± 9.7
|
46.10 ± 11.3
|
0.131
|
|
Gender (male/female)
|
18/12
|
26/15
|
0.293
|
|
Alanine aminotransferase (U/L)
|
444.9 ± 58.3
|
490.3 ± 66.2
|
0.614
|
|
Aspartate aminotransferase (U/L)
|
501.3 ± 87.6
|
536.1 ± 74.6
|
0.592
|
|
Total bilirubin (μmol/l)
|
332.8 ± 100.3
|
396.112 ± 87.3
|
0.007
|
|
Albumin (g/L)
|
32.56 ± 5.4
|
30.9 ± 4.11
|
0.009
|
|
HBsAg positive (n)
|
30
|
41
|
–
|
|
HBV DNA (log10 copies/mL)
|
4.44 ± 1.25
|
4.16 ± 1.62
|
0.024
|
|
Creatinine (μmol/L)
|
70.63 ± 26.9
|
79.65 ± 37.6
|
0.011
|
|
Prothrombin time (s)
|
24.1 ± 6.6
|
26.4 ± 9.8
|
0.044
|
|
International normalized ratio
|
2.31 ± 0.57
|
2.77 ± 0.55
|
0.056
|
|
IL-1β(pg/ml)
|
1.49 ± 0.63
|
1.57 ± 0.87
|
0.78
|
|
IL-18(pg/m)
|
287.33 ± 85.9
|
355.27 ± 100.14
|
0.007
|
- Abbreviations: ACLF acute-on-chronic liver failure, IL-1β, interleukin-1β, IL-18, interleukin-8
