Current diagnosis and management of Crohn’s disease in China: results from a multicenter prospective disease registry

Table 6 Logistic model for each correlation factors to baseline perianal disease (has perianal disease vs. no perianal disease)

Variable	OR	95% CI for OR	Parameter estimates (standard error)	Corresponding 95% CI	P value
Age (years)	0.957	0.937, 0.977	−0.044 (0.011)+	−0.065, −0.023	<.001*
Sex (male vs. female)	1.072	0.701, 1.638	0.069 (0.216)	−0.355, 0.493	0.749
BMI (18.5 - < 24 vs. < 18.5 kg/m²)	1.082	0.632, 1.854	0.079 (0.275)	−0.459, 0.617	0.773
BMI (≥24 vs. < 18.5 kg/m²)	1.795	0.688, 4.683	0.585 (0.489)+	−0.373, 1.544	0.231
Nicotine use (former vs. Never)	0.209	0.048, 0.904	−1.564 (0.747)+	−3.028, −0.100	0.036*
Nicotine use (current vs. Never)	0.460	0.187, 1.136	−0.776 (0.461)+	−1.679, 0.127	0.092
Alcohol use (former vs. Never)	0.822	0.292, 2.313	−0.196 (0.528)	−1.231, 0.839	0.710
Alcohol use (current vs. Never)	0.389	0.113, 1.341	−0.943 (0.631)+	−2.180, 0.293	0.135
Time from disease onset to enrollment (months)	0.996	0.992, 1.000	−0.004 (0.002)+	−0.008, − 0.000	0.036*
Time from initial definite diagnosis to enrollment (months)	0.993	0.986, 1.000	−0.007 (0.003)+	−0.014, − 0.000	0.039*
Disease behavior (B2 vs. B1)	0.514	0.320, 0.827	−0.665 (0.243)+	−1.141, − 0.190	0.006*
Disease behavior (B3 vs. B1)	0.755	0.453, 1.256	−0.282 (0.260)+	−0.791, 0.228	0.279
Disease behavior (B3 vs. B2)	1.468	0.814, 2.646	0.384 (0.301)+	−0.206, 0.973	0.202
Disease location (L3 vs. L1)	3.052	1.834, 5.079	1.116 (0.260)+	0.607, 1.6252	<.001*
Disease location (L3 vs. L2)	2.485	1.320, 4.681	0.911 (0.323)+	0.277, 1.544	0.005*

“No perianal disease” is the reference level. +: standard error is not larger than parameter estimates. *: P < 0.05. B1 non-stricturing non-penetrating, B2 stricturing, B3 penetrating, BMI body mass index, CI confidence interval, L1 terminal ileum, L2 colon, L3 ileocolon, OR odds ratio

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