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Table 3 Demographic and clinical characteristics - grouped by baseline surgery information

From: Current diagnosis and management of Crohn’s disease in China: results from a multicenter prospective disease registry

Variable

Total

Patients with surgery history

Patients without surgery history

P value

N (%)

499

119 (23.8%)

380 (76.2%)

 

Age (years), mean (SD)

32.3 (11.43)

37.3 (11.95)

30.8 (10.81)

< 0.0001

Male, n (%)

348

91 (76.5%)

257 (67.6%)

0.0670

BMI (kg/m2), mean (SD)

19.10 (3.198)

18.81 (3.119)

19.19 (3.223)

0.3898

Age at disease onset (years), mean (SD)

27.9 (10.63)

30.8 (10.98)

27.0 (10.37)

0.0006

Age group at disease onset (years), n (%)

   

0.0007

 N

499

119

380

 

  ≤ 16

29 (5.8%)

6 (5.0%)

23 (6.1%)

 

 17–39

401 (80.4%)

84 (70.6%)

317 (83.4%)

 

  ≥ 40

69 (13.8%)

29 (24.4%)

40 (10.5%)

 

Age at initial definite diagnosis (years), mean (SD)

30.6 (11.01)

34.1 (11.45)

29.5 (10.66)

< 0.0001

Time from disease onset to initial diagnosis (months), mean (SD)

32.0 (46.43)

39.4 (47.57)

29.6 (45.89)

0.0457

Time from initial diagnosis to enrollment (months), mean (SD)

20.6 (39.06)

39.3 (61.42)

14.8 (26.24)

< 0.0001

Time from disease onset to enrollment (months), mean (SD)

52.6 (59.08)

78.6 (73.29)

44.4 (51.32)

< 0.0001

Nicotine use history, n (%)

   

0.4698

 N

442

99

343

 

 Never used

382 (86.4%)

83 (83.8%)

299 (87.2%)

 

 Current user

36 (8.1%)

11 (11.1%)

25 (7.3%)

 

 Former user

24 (5.4%)

5 (5.1%)

19 (5.5%)

 

Alcohol use history, n (%)

   

0.0760

 N

443

99

344

 

 Never used

401 (90.5%)

84 (84.8%)

317 (92.2%)

 

 Current user

22 (5.0%)

8 (8.1%)

14 (4.1%)

 

 Former user

20 (4.5%)

7 (7.1%)

13 (3.8%)

 

Location, n (%)

   

0.4628

 N

493

115

378

 

 L1

137 (27.8%)

27 (23.5%)

110 (29.1%)

 

 L2

71 (14.4%)

21 (18.3%)

50 (13.2%)

 

 L3

277 (56.2%)

65 (56.5%)

212 (56.1%)

 

 L4

8 (1.6%)

2 (1.7%)

6 (1.6%)

 

Behavior, n (%)

   

< 0.0001

 N

495

115

380

 

 B1

247 (49.9%)

27 (23.5%)

220 (57.9%)

 

 B2

148 (29.9%)

38 (33.0%)

110 (28.9%)

 

 B3

100 (20.2%)

50 (43.5%)

50 (13.2%)

 

Perianal disease, n (%)

144 (28.9%)

20 (16.8%)

124 (32.6%)

0.0009

  1. B1 non-stricturing non-penetrating, B2 stricturing, B3 penetrating, BMI body mass index, L1 terminal ileum, L2 colon, L3 ileocolon, L4 upper gastrointestinal tract, SD standard deviation