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Table 3 Demographic and clinical characteristics - grouped by baseline surgery information

From: Current diagnosis and management of Crohn’s disease in China: results from a multicenter prospective disease registry

VariableTotalPatients with surgery historyPatients without surgery historyP value
N (%)499119 (23.8%)380 (76.2%) 
Age (years), mean (SD)32.3 (11.43)37.3 (11.95)30.8 (10.81)< 0.0001
Male, n (%)34891 (76.5%)257 (67.6%)0.0670
BMI (kg/m2), mean (SD)19.10 (3.198)18.81 (3.119)19.19 (3.223)0.3898
Age at disease onset (years), mean (SD)27.9 (10.63)30.8 (10.98)27.0 (10.37)0.0006
Age group at disease onset (years), n (%)   0.0007
 N499119380 
  ≤ 1629 (5.8%)6 (5.0%)23 (6.1%) 
 17–39401 (80.4%)84 (70.6%)317 (83.4%) 
  ≥ 4069 (13.8%)29 (24.4%)40 (10.5%) 
Age at initial definite diagnosis (years), mean (SD)30.6 (11.01)34.1 (11.45)29.5 (10.66)< 0.0001
Time from disease onset to initial diagnosis (months), mean (SD)32.0 (46.43)39.4 (47.57)29.6 (45.89)0.0457
Time from initial diagnosis to enrollment (months), mean (SD)20.6 (39.06)39.3 (61.42)14.8 (26.24)< 0.0001
Time from disease onset to enrollment (months), mean (SD)52.6 (59.08)78.6 (73.29)44.4 (51.32)< 0.0001
Nicotine use history, n (%)   0.4698
 N44299343 
 Never used382 (86.4%)83 (83.8%)299 (87.2%) 
 Current user36 (8.1%)11 (11.1%)25 (7.3%) 
 Former user24 (5.4%)5 (5.1%)19 (5.5%) 
Alcohol use history, n (%)   0.0760
 N44399344 
 Never used401 (90.5%)84 (84.8%)317 (92.2%) 
 Current user22 (5.0%)8 (8.1%)14 (4.1%) 
 Former user20 (4.5%)7 (7.1%)13 (3.8%) 
Location, n (%)   0.4628
 N493115378 
 L1137 (27.8%)27 (23.5%)110 (29.1%) 
 L271 (14.4%)21 (18.3%)50 (13.2%) 
 L3277 (56.2%)65 (56.5%)212 (56.1%) 
 L48 (1.6%)2 (1.7%)6 (1.6%) 
Behavior, n (%)   < 0.0001
 N495115380 
 B1247 (49.9%)27 (23.5%)220 (57.9%) 
 B2148 (29.9%)38 (33.0%)110 (28.9%) 
 B3100 (20.2%)50 (43.5%)50 (13.2%) 
Perianal disease, n (%)144 (28.9%)20 (16.8%)124 (32.6%)0.0009
  1. B1 non-stricturing non-penetrating, B2 stricturing, B3 penetrating, BMI body mass index, L1 terminal ileum, L2 colon, L3 ileocolon, L4 upper gastrointestinal tract, SD standard deviation