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Table 3 Variable analysis of factors affecting eradication efficacy

From: Cefuroxime, levofloxacin, esomeprazole, and bismuth as first-line therapy for eradicating Helicobacter pylori in patients allergic to penicillin

Variable, n/N (%)Univariable analysisMultivariable analysis
Eradication efficacy (n = 147)P valueOR (95% CI)P value
Age
 < 35 years40/45 (88.9)0.991  
 35–55 years59/67 (88.1)  
 > 55 years31/35 (88.6)  
Gender:
 female61/68 (89.7)0.655  
 male69/79 (87.3)
Body mass index:
 < 22.0 kg/m238/42 (90.5)0.856  
 22.0–25.0 kg/m260/68 (88.2)
 > 25.0 kg/m232/37 (86.5)
Cigarette smoking:
 yes19/22 (86.4)0.742  
 no111/125 (88.8)
Alcohol drinking:
 yes21/25 (84.0)0.447  
 no109/122 (89.3)
Diagnosis:
 PUD14/14 (100.0)0.361  
 NUD53/61 (86.9)
 UID63/72 (87.5)
H. pylori density a:
 +25/29 (86.2)0.929  
 ++ +++24/27 (88.9)17/19 (89.4)
Compliance:
 good128/142 (90.1)< 0.00118.0000.013
 poor2/5 (40.0)(1.843–175.775) 
Cefuroxime resistance b:
 susceptible56/61 (91.8)0.00236.000 
 resistant1/3 (33.3)(2.500–518.371)0.008
Levofloxacin resistance b:
 susceptible36/38 (94.7)0.079  
 resistant21/26 (80.8)
  1. CI Confidence interval, NUD Non-ulcer dyspepsia, OR Odds ratio, PUD Peptic ulcer disease, UID Uninvestigated dyspepsia
  2. aData for H. pylori density were available in 75 patients
  3. bData for H. pylori antimicrobial sensitivity were available in 64 patients