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Table 2 Chemotherapy induced diarrhoea severity based on Common Terminology Criteria for Adverse Event version 3.0 (CTCAEv3.0) in probiotics and placebo groups

From: A randomized double-blind placebo-controlled trial of probiotics in post-surgical colorectal cancer

CTCAE Diarrhea GradingPre-treatmentPost- treatment
Probiotic (n = 6)
 Grade 1 (< 4 times/day)53
 Grade 2 (4–6 times/day)12
 Grade 3 (>  7 times/day) 1
 Grade 4 (life-threatening)  
 Grade 5 (death)  
Placebo (n = 5)
 Grade 1 (< 4 times/day)31
 Grade 2 (4–6 times/day)23
 Grade 3 (>  7 times/day) 1
 Grade 4 (life-threatening)  
 Grade 5 (death)