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Table 5 Comparison of SVM, LRA, ANN and APACHE II score for predicting MOF

From: Development and validation of three machine-learning models for predicting multiple organ failure in moderately severe and severe acute pancreatitis

Variable SVM (95% CI) LRA (95% CI) ANN (95% CI) APACHE II score (95% CI) P value
SEN 75.00%(63.16–84.13%) 79.17%(67.67–87.50%) 86.11%(75.48–92.78%) 80.56%(69.20–88.59%) 0.413
SPE 81.68%(75.30–86.75%)b, c 77.49%(70.78–83.07%) 65.45%(58.19–72.07%)a 65.45%(58.19–72.07%)a < 0.001
FPR 18.32%(12.84–23.81%)b, c 22.51%(16.59–28.43%) 34.55%(27.79–41.31%)a 34.55%(27.79–41.31%)a < 0.001
FNR 25.00%(15.00–35.00%) 20.83%(11.45–32.21%) 13.89%(5.90–21.88%) 19.44%(10.30–28.58%) 0.413
PPV 60.67%(49.72–70.69%)c 57.00%(46.72–66.73%) 48.44%(39.58–57.39%) 46.77%(37.83–55.92%) 0.129
NPV 89.66%(83.91–93.58%) 90.80%(85.01–94.58%) 92.59%(86.45–96.16%) 89.93%(83.38–94.18%) 0.827
Accuracy 79.85%(74.10–83.80%)b, c 77.95%(72.94–82.96%) 71.10%(65.62–76.58%) 69.58%(64.02–75.14%)a 0.014
AUC 0.840 (0.783–0.896) 0.832 (0.773–0.890) 0.834 (0.777–0.890) 0.814 (0.759–0.869)
  1. aCompared with LRA, P < 0.05
  2. bCompared with ANN, P < 0.05
  3. cCompared with APACHE II score, P < 0.05
  4. P value denoted the overall statistical result for the three models and APACHE II score
  5. Entries in boldface showed significant difference