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Table 4 Association between HLA-DQB1*02 gene dosage and clinical and analytical features

From: Influence of HLA on clinical and analytical features of pediatric celiac disease

 

Bivariate analysis

Multivariate analysis

OR (CI 95%)

p

OR (CI 95%)

p

Clinical presentationa

2.01 (1.04–3.91)

0.04

2.31 (1.01–5.32)*

0.05*

Histological severityb

2.43 (1.13–5.26)

0.02

2.54 (1.16–5.52)**

0.02**

Serologyc

6.64 (0.84–52.7)

0.07

6.09 (0.74–49.87)**

0.09**

Anti-TG2 leveld

0.91 (0.45–1.81)

0.78

0.91 (0.45–1.61)**

0.80**

  1. *corrected by age at onset. When corrected by sex and age: OR (95% CI) = 2.2 (0.95–5.10). p = 0.066;
  2. **corrected by age at onset and sex
  3. ORs are referred to a classical vs. non-classical presentation; b Marsh 3b/Marsh 3c vs. others; c positive vs. negative anti-TG2/EMA, excluding IgA deficient patients; d anti-TG2 ≤ 10 vs. > 10 the upper limit of normality
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BMC Gastroenterology

ISSN: 1471-230X

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