Table 1 Baseline characteristics of patients with MPA and GPA (N = 132)
Variables | Values |
|---|---|
Demographic data | |
Age at diagnosis (year old) | 57.2 ± 14.7 |
Male gender (N, (%)) | 40 (30.3) |
AAV variants (N, (%)) | |
MPA | 91 (68.9) |
GPA | 41 (31.1) |
ANCA positivity (N, (%)) | 112 (84.8) |
Activity and prognostic factor at diagnosis | |
BVAS | 13.1 ± 7.2 |
FFS (2009) | 1.4 ± 1.0 |
FFS (2009) ≥ 2 (N, (%)) | 57 (43.2) |
Laboratory results at diagnosis | |
White blood cell (/mm3) | 9538.3 ± 3940.5 |
Haemoglobin (g/dL) | 12.0 ± 1.2 |
Platelet × 103 (/mm3) | 331.8 ± 144.7 |
Prothrombin time (INR) | 1.0 ± 0.1 |
Fasting glucose (mg/dL) | 116.8 ± 44.6 |
Blood urea nitrogen (mg/dL) | 28.1 ± 25.3 |
Creatinine (mg/dL) | 1.9 ± 2.1 |
Protein (g/dL) | 6.7 ± 0.9 |
Serum albumin (g/dL) | 3.5 ± 0.8 |
Alkaline phosphatase (IU/L) | 93.7 ± 94.3 |
Aspartate aminotransferase (IU/L) | 23.2 ± 26.5 |
Alanine aminotransferase (IU/L) | 23.4 ± 39.3 |
Total bilirubin (mg/dL) | 0.7 ± 1.6 |
Total cholesterol (mg/dL) | 171.4 ± 50.4 |
Acute reactants at diagnosis | |
Erythrocyte sedimentation rate (mm/hr) | 62.8 ± 38.0 |
C-reactive protein (mg/L) | 44.0 ± 56.8 |
Liver fibrosis index at diagnosis | |
FIB-4 | 1.1 ± 0.9 |
FIB-4 ≥ 1.45 (N, (%)) | 27 (20.5) |
Comorbidities except items of BVAS or FFS (2009) at diagnosisa (N, (%)) | |
DM | 26 (19.7) |
HTN | 61 (46.2) |
Follow-up duration (months) | 52.4 ± 52.2 |
Death (N, (%)) | 15 (11.4%) |