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Table 4 Monofactorial analysis of liver inflammation improvement

From: Histological improvement in chronic hepatitis B patients treated with bicyclol: real world experience

Factor I Improved n (%) Not improved n (%) P Unadjusted OR (95%CI)
Treatment course of bicyclol (weeks)    0.001 6.750 (2.300, 19.811)
  ≥ 48 21 (70.00) 9 (30.00)   
  < 48 10 (25.00) 30 (75.00)   
Age (years)    0.211 2.639 (0.577, 12.064)
  ≥ 50 5 (62.50) 3 (37.50)   
  < 50 24 (38.71) 38 (61.29)   
Sex    0.176 2.816 (0.705, 6.777)
 Female 9 (56.25) 7 (43.75)   
 Male 20 (37.04) 34 (62.96)   
ALT (U/L)    0.024 0.301 (0.107, 0.851)
  ≥ 40 15 (31.91) 32 (68.09)   
  < 40 14 (60.87) 9 (39.13)   
HBeAg    0.184 1.923 (0.733, 5.043)
 Negative 16 (50.00) 16 (50.00)   
 Positive 13 (34.21) 25 (65.79)   
HBV-DNA    0.341 0.532 (0.146, 1.948)
  ≥ 105 IU/mL 23 (38.98) 36 (61.02)   
  < 105 IU/mL 6 (54.55) 5 (45.45)