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Table 2 Biochemical, virological, serological responses and APRI change after bicyclol treatment

From: Histological improvement in chronic hepatitis B patients treated with bicyclol: real world experience

variable

All patients (n = 123)

Normal ALT (n = 38)

Elevated ALT (n = 85)

ALT≤1 × upper limit of normal, n(%)

107 (87.0)

37 (97.4)

70 (82.4)

HBeAg loss, n(%)

11 (16.7)

2 (22.2)

9 (15.8)

HBV DNA (mean ± SD), log10IU/ml

 Pre-treatment

5.99 ± 1.76

4.43 ± 1.79

6.67 ± 1.24

 Post-treatment

5.20 ± 1.77*

4.23 ± 1.66

5.76 ± 1.59*

  1. *Compared to pretreatment level, P < 0.05